PDB entry 2zke

View 2zke on RCSB PDB site
Description: Crystal structure of the SRA domain of mouse Np95 in complex with hemi-methylated CpG DNA
Class: ligase
Keywords: Protein-DNA interaction, Cell cycle, Developmental protein, DNA damage, DNA repair, DNA-binding, Ligase, Metal-binding, Nucleus, Phosphoprotein, Transcription, Transcription regulation, Ubl conjugation pathway, Zinc-finger
Deposited on 2008-03-19, released 2008-09-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.221
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: E3 ubiquitin-protein ligase UHRF1
  Species: Mus musculus [TaxId:10090]
  Gene: Uhrf1, Np95
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q8VDF2 (0-209)
    • engineered (0)
  Domains in SCOPe 2.08: d2zkea_
• Chain 'C':
  Compound: DNA (5'-d(*dcp*dtp*dap*dcp*dcp*dgp*dgp*dap*dtp*dtp*dgp*dc)-3')
  Species: synthetic, synthetic
  
• Chain 'D':
  Compound: DNA (5'-d(*dgp*dcp*dap*dap*dtp*dcp*(5cm)p*dgp*dgp*dtp*dap*dg)-3')
  Species: synthetic, synthetic
  
• Heterogens: HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2zkeA (A:)
  sgmacvgrttectivpanhfgpipgvpvgtmwrfrvqvsesgvhrphvagihgrsndgay
  slvlaggyeddvdngnyftytgsggrdlsgnkrtagqssdqkltnnnralalnchspine
  kgaeaedwrqgkpvrvvrnmkggkhskyapaegnrydgiykvvkywpergksgflvwryl
  lrrddtepepwtregkdrtrqlgltmqype
  

  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  No sequence available.