PDB entry 2zi8

View 2zi8 on RCSB PDB site
Description: Crystal structure of the HsaC extradiol dioxygenase from M. tuberculosis in complex with 3,4-dihydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione (DHSA)
Class: oxidoreductase
Keywords: DHSA, HsaC, extradiol dioxygenase, Mycobacterium tuberculosis, Aromatic hydrocarbons catabolism, Iron, Oxidoreductase
Deposited on 2008-02-13, released 2009-02-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-04-08, with a file datestamp of 2020-04-03.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: probable biphenyl-2,3-diol 1,2-dioxygenase bphc
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2zi8a1, d2zi8a2
  • Chain 'B':
    Compound: probable biphenyl-2,3-diol 1,2-dioxygenase bphc
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2zi8b1, d2zi8b2
  • Heterogens: FE2, SDT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2zi8A (A:)
msirslgylrieatdmaawreyglkvlgmvegkgapegalylrmddfparlvvvpgehdr
lleagwecanaeglqeirnrldlegtpykeataaeladrrvdemirfadpsgnclevfhg
talehrrvvspyghrfvtgeqgmghvvlstrddaealhfyrdvlgfrlrdsmrlppqmvg
rpadgppawlrffgcnprhhslaflpmptssgivhlmveveqaddvglcldralrrkvpm
satlgrhvndlmlsfymktpggfdiefgcegrqvddrdwiarestavslwghdftvgarg

    Sequence, based on observed residues (ATOM records): (download) 
    >2zi8A (A:)
msirslgylrieatdmaawreyglkvlgmvegkgapegalylrmddfparlvvvpgehdr
lleagwecanaeglqeirnrldlegtpykeataaeladrrvdemirfadpsgnclevfhg
talehrrvvspyghrfvtgeqgmghvvlstrddaealhfyrdvlgfrlrdsmrlppqmvg
rpadgppawlrffgcnprhhslaflpmptssgivhlmveveqaddvglcldralrrkvpm
satlgrhvndlmlsfymktpggfdiefgcegrqvddrdwiarestavslwghdftvgar

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2zi8B (B:)
msirslgylrieatdmaawreyglkvlgmvegkgapegalylrmddfparlvvvpgehdr
lleagwecanaeglqeirnrldlegtpykeataaeladrrvdemirfadpsgnclevfhg
talehrrvvspyghrfvtgeqgmghvvlstrddaealhfyrdvlgfrlrdsmrlppqmvg
rpadgppawlrffgcnprhhslaflpmptssgivhlmveveqaddvglcldralrrkvpm
satlgrhvndlmlsfymktpggfdiefgcegrqvddrdwiarestavslwghdftvgarg

    Sequence, based on observed residues (ATOM records): (download) 
    >2zi8B (B:)
msirslgylrieatdmaawreyglkvlgmvegkgapegalylrmddfparlvvvpgehdr
lleagwecanaeglqeirnrldlegtpykeataaeladrrvdemirfadpsgnclevfhg
talehrrvvspyghrfvtgeqgmghvvlstrddaealhfyrdvlgfrlrdsmrlppqmvg
rpadgppawlrffgcnprhhslaflpmptssgivhlmveveqaddvglcldralrrkvpm
satlgrhvndlmlsfymktpggfdiefgcegrqvddrdwiarestavslwghdftvga