PDB entry 2zet

View 2zet on RCSB PDB site
Description: Crystal structure of the small GTPase Rab27B complexed with the Slp homology domain of Slac2-a/melanophilin
Class: signaling protein
Keywords: COMPLEX, GTP-BINDING PROTEIN, GTPASE, G-PROTEIN, RAB, RAB27B, EFFECTOR, MELANOPHILIN, Slp homology domain, Acetylation, Lipoprotein, Membrane, Methylation, Nucleotide-binding, Prenylation, Coiled coil, Metal-binding, Zinc, Zinc-finger, Structural Genomics, NPPSFA, National Project on Protein Structural and Functional Analyses, RIKEN Structural Genomics/Proteomics Initiative, RSGI, SIGNALING PROTEIN
Deposited on 2007-12-17, released 2008-09-30
The last revision prior to the SCOPe 2.05 freeze date was dated 2010-01-05, with a file datestamp of 2009-12-31.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.247
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ras-related protein Rab-27B
    Species: Mus musculus [TaxId:10090]
    Gene: RAB27B
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99P58
      • engineered (79)
    Domains in SCOPe 2.05: d2zeta_
  • Chain 'B':
    Compound: Ras-related protein Rab-27B
    Species: Mus musculus [TaxId:10090]
    Gene: RAB27B
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99P58
      • engineered (79)
    Domains in SCOPe 2.05: d2zetb_
  • Chain 'C':
    Compound: Melanophilin
    Species: Mus musculus [TaxId:10090]
    Gene: Slac2a
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Melanophilin
    Species: Mus musculus [TaxId:10090]
    Gene: Slac2a
    Database cross-references and differences (RAF-indexed):
  • Heterogens: MG, GTP, ZN, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2zetA (A:)
gsmtdgdydylikllalgdsgvgkttflyrytdnkfnpkfittvgidfrekrvvydtqga
dgasgkafkvhlqlwdtaglerfrslttaffrdamgfllmfdltsqqsflnvrnwmsqlq
anaycenpdivlignkadlpdqrevnerqarelaekygipyfetsaatgqnveksvetll
dlimkrmekcvektqvpdtvngg

    Sequence, based on observed residues (ATOM records): (download) 
    >2zetA (A:)
dydylikllalgdsgvgkttflyrytdnkfnpkfittvgidfrekrvvydtqgasgkafk
vhlqlwdtaglerfrslttaffrdamgfllmfdltsqqsflnvrnwmsqlqanaycenpd
ivlignkadlpdqrevnerqarelaekygipyfetsaatgqnveksvetlldlimkrmek
c

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2zetB (B:)
gsmtdgdydylikllalgdsgvgkttflyrytdnkfnpkfittvgidfrekrvvydtqga
dgasgkafkvhlqlwdtaglerfrslttaffrdamgfllmfdltsqqsflnvrnwmsqlq
anaycenpdivlignkadlpdqrevnerqarelaekygipyfetsaatgqnveksvetll
dlimkrmekcvektqvpdtvngg

    Sequence, based on observed residues (ATOM records): (download) 
    >2zetB (B:)
dydylikllalgdsgvgkttflyrytdnkfnpkfittvgidfrekrvvydtfkvhlqlwd
taglerfrslttaffrdamgfllmfdltsqqsflnvrnwmsqlqanaycenpdivlignk
adlpdqrevnerqarelaekygipyfetsaatgqnveksvetlldlimkrmekc

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.