PDB entry 2zec
View 2zec on RCSB PDB site
Description: Potent, Nonpeptide Inhibitors of Human Mast Cell Tryptase
Class: hydrolase
Keywords: tryptase, serine protease, Hydrolase
Deposited on
2007-12-08, released
2008-12-09
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-10-11, with a file datestamp of
2017-10-06.
Experiment type: XRAY
Resolution: 2.06 Å
R-factor: N/A
AEROSPACI score: 0.29
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Tryptase beta 2
Species: Homo sapiens [TaxId:9606]
Gene: TPSB2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2zeca_ - Chain 'B':
Compound: Tryptase beta 2
Species: Homo sapiens [TaxId:9606]
Gene: TPSB2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2zecb_ - Chain 'C':
Compound: Tryptase beta 2
Species: Homo sapiens [TaxId:9606]
Gene: TPSB2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2zecc_ - Chain 'D':
Compound: Tryptase beta 2
Species: Homo sapiens [TaxId:9606]
Gene: TPSB2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2zecd_ - Heterogens: 11N, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>2zecA (A:)
ivggqeaprskwpwqvslrvhgpywmhfcggslihpqwvltaahcvgpdvkdlaalrvql
reqhlyyqdqllpvsriivhpqfytaqigadialleleepvkvsshvhtvtlppasetfp
pgmpcwvtgwgdvdnderlpppfplkqvkvpimenhicdakyhlgaytgddvrivrddml
cagntrrdscqgdsggplvckvngtwlqagvvswgegcaqpnrpgiytrvtyyldwihhy
vpk
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>2zecB (B:)
ivggqeaprskwpwqvslrvhgpywmhfcggslihpqwvltaahcvgpdvkdlaalrvql
reqhlyyqdqllpvsriivhpqfytaqigadialleleepvkvsshvhtvtlppasetfp
pgmpcwvtgwgdvdnderlpppfplkqvkvpimenhicdakyhlgaytgddvrivrddml
cagntrrdscqgdsggplvckvngtwlqagvvswgegcaqpnrpgiytrvtyyldwihhy
vpk
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>2zecC (C:)
ivggqeaprskwpwqvslrvhgpywmhfcggslihpqwvltaahcvgpdvkdlaalrvql
reqhlyyqdqllpvsriivhpqfytaqigadialleleepvkvsshvhtvtlppasetfp
pgmpcwvtgwgdvdnderlpppfplkqvkvpimenhicdakyhlgaytgddvrivrddml
cagntrrdscqgdsggplvckvngtwlqagvvswgegcaqpnrpgiytrvtyyldwihhy
vpk
- Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)
>2zecD (D:)
ivggqeaprskwpwqvslrvhgpywmhfcggslihpqwvltaahcvgpdvkdlaalrvql
reqhlyyqdqllpvsriivhpqfytaqigadialleleepvkvsshvhtvtlppasetfp
pgmpcwvtgwgdvdnderlpppfplkqvkvpimenhicdakyhlgaytgddvrivrddml
cagntrrdscqgdsggplvckvngtwlqagvvswgegcaqpnrpgiytrvtyyldwihhy
vpk