PDB entry 2zeb

View 2zeb on RCSB PDB site
Description: Potent, Nonpeptide Inhibitors of Human Mast Cell Tryptase
Class: hydrolase
Keywords: tryptase, serine protease, Hydrolase
Deposited on 2007-12-08, released 2008-12-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2008-12-09, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.172
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tryptase beta 2
    Species: Homo sapiens [TaxId:9606]
    Gene: TPSB2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2zeba_
  • Chain 'B':
    Compound: Tryptase beta 2
    Species: Homo sapiens [TaxId:9606]
    Gene: TPSB2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2zebb_
  • Chain 'C':
    Compound: Tryptase beta 2
    Species: Homo sapiens [TaxId:9606]
    Gene: TPSB2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2zebc_
  • Chain 'D':
    Compound: Tryptase beta 2
    Species: Homo sapiens [TaxId:9606]
    Gene: TPSB2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2zebd_
  • Heterogens: 11M, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2zebA (A:)
ivggqeaprskwpwqvslrvhgpywmhfcggslihpqwvltaahcvgpdvkdlaalrvql
reqhlyyqdqllpvsriivhpqfytaqigadialleleepvkvsshvhtvtlppasetfp
pgmpcwvtgwgdvdnderlpppfplkqvkvpimenhicdakyhlgaytgddvrivrddml
cagntrrdscqgdsggplvckvngtwlqagvvswgegcaqpnrpgiytrvtyyldwihhy
vpk

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2zebB (B:)
ivggqeaprskwpwqvslrvhgpywmhfcggslihpqwvltaahcvgpdvkdlaalrvql
reqhlyyqdqllpvsriivhpqfytaqigadialleleepvkvsshvhtvtlppasetfp
pgmpcwvtgwgdvdnderlpppfplkqvkvpimenhicdakyhlgaytgddvrivrddml
cagntrrdscqgdsggplvckvngtwlqagvvswgegcaqpnrpgiytrvtyyldwihhy
vpk

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2zebC (C:)
ivggqeaprskwpwqvslrvhgpywmhfcggslihpqwvltaahcvgpdvkdlaalrvql
reqhlyyqdqllpvsriivhpqfytaqigadialleleepvkvsshvhtvtlppasetfp
pgmpcwvtgwgdvdnderlpppfplkqvkvpimenhicdakyhlgaytgddvrivrddml
cagntrrdscqgdsggplvckvngtwlqagvvswgegcaqpnrpgiytrvtyyldwihhy
vpk

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2zebD (D:)
ivggqeaprskwpwqvslrvhgpywmhfcggslihpqwvltaahcvgpdvkdlaalrvql
reqhlyyqdqllpvsriivhpqfytaqigadialleleepvkvsshvhtvtlppasetfp
pgmpcwvtgwgdvdnderlpppfplkqvkvpimenhicdakyhlgaytgddvrivrddml
cagntrrdscqgdsggplvckvngtwlqagvvswgegcaqpnrpgiytrvtyyldwihhy
vpk