PDB entry 2zea

View 2zea on RCSB PDB site
Description: Crystal structure of Alcaligenes faecalis D-3-hydroxybutyrate dehydrogenase in complex with NAD+ and acetate
Class: oxidoreductase
Keywords: NAD dependent enzyme, hydroxybutyrate dehydrogenase, ketone bodies, OXIDOREDUCTASE
Deposited on 2007-12-07, released 2008-06-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-02-29, with a file datestamp of 2012-02-24.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.191
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: D-3-hydroxybutyrate dehydrogenase
    Species: Alcaligenes faecalis [TaxId:511]
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZEA (0-259)
    Domains in SCOPe 2.07: d2zeaa_
  • Chain 'B':
    Compound: D-3-hydroxybutyrate dehydrogenase
    Species: Alcaligenes faecalis [TaxId:511]
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZEA (0-259)
    Domains in SCOPe 2.07: d2zeab_
  • Chain 'C':
    Compound: D-3-hydroxybutyrate dehydrogenase
    Species: Alcaligenes faecalis [TaxId:511]
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZEA (0-259)
    Domains in SCOPe 2.07: d2zeac_
  • Chain 'D':
    Compound: D-3-hydroxybutyrate dehydrogenase
    Species: Alcaligenes faecalis [TaxId:511]
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZEA (0-259)
    Domains in SCOPe 2.07: d2zead_
  • Heterogens: ACT, CA, CL, NAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2zeaA (A:)
    mlkgkkavvtgstsgiglamatelakagadvvingfgqpediererstleskfgvkayyl
    nadlsdaqatrdfiakaaealggldilvnnagiqhtapieefpvdkwnaiialnlsavfh
    gtaaalpimqkqgwgriiniasahglvasvnksayvaakhgvvgltkvtalenagkgitc
    naicpgwvrtplvekqieaisqqkgidieaaarellaekqpslqfvtpeqlggaavflss
    aaadqmtgttlsldggwtar
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2zeaB (B:)
    mlkgkkavvtgstsgiglamatelakagadvvingfgqpediererstleskfgvkayyl
    nadlsdaqatrdfiakaaealggldilvnnagiqhtapieefpvdkwnaiialnlsavfh
    gtaaalpimqkqgwgriiniasahglvasvnksayvaakhgvvgltkvtalenagkgitc
    naicpgwvrtplvekqieaisqqkgidieaaarellaekqpslqfvtpeqlggaavflss
    aaadqmtgttlsldggwtar
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2zeaC (C:)
    mlkgkkavvtgstsgiglamatelakagadvvingfgqpediererstleskfgvkayyl
    nadlsdaqatrdfiakaaealggldilvnnagiqhtapieefpvdkwnaiialnlsavfh
    gtaaalpimqkqgwgriiniasahglvasvnksayvaakhgvvgltkvtalenagkgitc
    naicpgwvrtplvekqieaisqqkgidieaaarellaekqpslqfvtpeqlggaavflss
    aaadqmtgttlsldggwtar
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2zeaD (D:)
    mlkgkkavvtgstsgiglamatelakagadvvingfgqpediererstleskfgvkayyl
    nadlsdaqatrdfiakaaealggldilvnnagiqhtapieefpvdkwnaiialnlsavfh
    gtaaalpimqkqgwgriiniasahglvasvnksayvaakhgvvgltkvtalenagkgitc
    naicpgwvrtplvekqieaisqqkgidieaaarellaekqpslqfvtpeqlggaavflss
    aaadqmtgttlsldggwtar