PDB entry 2zdw

View 2zdw on RCSB PDB site
Description: Crystal Structure of H61A mutant TTHA0252 from Thermus thermophilus HB8
Class: hydrolase
Keywords: METALLO BETA LACTAMASE FOLD, HYDROLASE, Structural Genomics, NPPSFA, National Project on Protein Structural and Functional Analyses, RIKEN Structural Genomics/Proteomics Initiative, RSGI
Deposited on 2007-11-30, released 2008-11-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-08-04, with a file datestamp of 2009-07-31.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.249
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: metallo-beta-lactamase superfamily protein
    Species: Thermus thermophilus [TaxId:274]
    Gene: TTHA0252
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5SLP1 (0-430)
      • engineered (60)
    Domains in SCOPe 2.08: d2zdwa_
  • Chain 'B':
    Compound: metallo-beta-lactamase superfamily protein
    Species: Thermus thermophilus [TaxId:274]
    Gene: TTHA0252
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5SLP1 (0-430)
      • engineered (60)
    Domains in SCOPe 2.08: d2zdwb_
  • Chain 'C':
    Compound: metallo-beta-lactamase superfamily protein
    Species: Thermus thermophilus [TaxId:274]
    Gene: TTHA0252
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5SLP1 (0-430)
      • engineered (60)
    Domains in SCOPe 2.08: d2zdwc_
  • Chain 'D':
    Compound: metallo-beta-lactamase superfamily protein
    Species: Thermus thermophilus [TaxId:274]
    Gene: TTHA0252
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5SLP1 (0-430)
      • engineered (60)
    Domains in SCOPe 2.08: d2zdwd_
  • Heterogens: SO4, ZN, FLC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2zdwA (A:)
mrivpfgaarevtgsahlllaggrrvlldcgmfqgkeearnhapfgfdpkevdavlltha
aldhvgrlpklfregyrgpvyatratvllmeivledalkvmdepffgpedveealghlrp
leygewlrlgalslafgqaghlpgsafvvaqgegrtlvysgdlgnrekdvlpdpslppla
dlvlaegtygdrphrpyretvrefleilektlsqggkvliptfaveraqeilyvlythgh
rlprapiyldspmagrvlslyprlvryfseevqahflqgknpfrpaglevvehteaskal
nrapgpmvvlagsgmlaggrilhhlkhglsdprnalvfvgyqpqgglgaeiiarppavri
lgeevplrasvhtlggfsghagqdelldwlqgeprvvlvhgeeekllalgkllalrgqev
slarfgegvpv

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2zdwB (B:)
mrivpfgaarevtgsahlllaggrrvlldcgmfqgkeearnhapfgfdpkevdavlltha
aldhvgrlpklfregyrgpvyatratvllmeivledalkvmdepffgpedveealghlrp
leygewlrlgalslafgqaghlpgsafvvaqgegrtlvysgdlgnrekdvlpdpslppla
dlvlaegtygdrphrpyretvrefleilektlsqggkvliptfaveraqeilyvlythgh
rlprapiyldspmagrvlslyprlvryfseevqahflqgknpfrpaglevvehteaskal
nrapgpmvvlagsgmlaggrilhhlkhglsdprnalvfvgyqpqgglgaeiiarppavri
lgeevplrasvhtlggfsghagqdelldwlqgeprvvlvhgeeekllalgkllalrgqev
slarfgegvpv

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2zdwC (C:)
mrivpfgaarevtgsahlllaggrrvlldcgmfqgkeearnhapfgfdpkevdavlltha
aldhvgrlpklfregyrgpvyatratvllmeivledalkvmdepffgpedveealghlrp
leygewlrlgalslafgqaghlpgsafvvaqgegrtlvysgdlgnrekdvlpdpslppla
dlvlaegtygdrphrpyretvrefleilektlsqggkvliptfaveraqeilyvlythgh
rlprapiyldspmagrvlslyprlvryfseevqahflqgknpfrpaglevvehteaskal
nrapgpmvvlagsgmlaggrilhhlkhglsdprnalvfvgyqpqgglgaeiiarppavri
lgeevplrasvhtlggfsghagqdelldwlqgeprvvlvhgeeekllalgkllalrgqev
slarfgegvpv

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2zdwD (D:)
mrivpfgaarevtgsahlllaggrrvlldcgmfqgkeearnhapfgfdpkevdavlltha
aldhvgrlpklfregyrgpvyatratvllmeivledalkvmdepffgpedveealghlrp
leygewlrlgalslafgqaghlpgsafvvaqgegrtlvysgdlgnrekdvlpdpslppla
dlvlaegtygdrphrpyretvrefleilektlsqggkvliptfaveraqeilyvlythgh
rlprapiyldspmagrvlslyprlvryfseevqahflqgknpfrpaglevvehteaskal
nrapgpmvvlagsgmlaggrilhhlkhglsdprnalvfvgyqpqgglgaeiiarppavri
lgeevplrasvhtlggfsghagqdelldwlqgeprvvlvhgeeekllalgkllalrgqev
slarfgegvpv