PDB entry 2zdu

View 2zdu on RCSB PDB site
Description: Crystal Structure of human JNK3 complexed with an isoquinolone inhibitor
Class: transferase
Keywords: PROTEIN KINASE, Alternative splicing, ATP-binding, Chromosomal rearrangement, Cytoplasm, Epilepsy, Nucleotide-binding, Phosphoprotein, Serine/threonine-protein kinase, Transferase
Deposited on 2007-11-27, released 2008-09-23
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.241
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 10
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d2zdua_
  • Heterogens: 446, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2zduA (A:)
mskskvdnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrp
fqnqthakrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviq
meldhermsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagtsf
mmtpyvvtryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieq
lgtpcpefmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardllsk
mlvidpakrisvddalqhpyinvwydpaeveapppqiydkqlderehtieewkeliykev
mnse

    Sequence, based on observed residues (ATOM records): (download) 
    >2zduA (A:)
nqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqtha
krayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldher
msyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglavtryyrapevilgm
gykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpefmkklqptvrnyv
enrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpakrisvddalqhpy
invwydpaevearehtieewkeliykevmn