PDB entry 2zc6

View 2zc6 on RCSB PDB site
Description: Penicillin-binding protein 1A (PBP 1A) acyl-enzyme complex (tebipenem) from Streptococcus pneumoniae
Class: biosynthetic protein
Keywords: PEPTIDOGLYCAN SYNTHESIS, CELL WALL, PENICILLIN-BINDING, ANTIBIOTICS, TEBIPENEM, Antibiotic resistance, Cell shape, Cell wall biogenesis/degradation, Multifunctional enzyme, Secreted, BIOSYNTHETIC PROTEIN
Deposited on 2007-11-02, released 2008-04-08
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.23
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: penicillin-binding protein 1a
    Species: Streptococcus pneumoniae
    Gene: pbpA, exp2
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: penicillin-binding protein 1a
    Species: Streptococcus pneumoniae
    Gene: pbp1a
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q549Y6
      • engineered (281)
    Domains in SCOPe 2.03: d2zc6b_
  • Chain 'C':
    Compound: penicillin-binding protein 1a
    Species: Streptococcus pneumoniae
    Gene: pbpA, exp2
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: penicillin-binding protein 1a
    Species: Streptococcus pneumoniae
    Gene: pbp1a
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q549Y6
      • engineered (281)
    Domains in SCOPe 2.03: d2zc6d_
  • Heterogens: ZN, TEB, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2zc6B (B:)
sasnypaymdnylkevinqveeetgynllttgmdvytnvdqeaqkhlwdiyntdeyvayp
ddelqvastivdvsngkviaqlgarhqssnvsfginqavetnrdwgstmkpitdyapale
ygvydstativhdepynypgtntpvynwdrgyfgnitlqyalqqsrnvpavetlnkvgln
raktflnglgidypsihysnaissnttesdkkygassekmaaayaafanggtyykpmyih
kvvfsdgsekefsnvgtramkettaymmtdmmktvlsygtgqnaylawlpqagktgtsny
tdeeienhiktsqfvapdelfagytrkysmavwtgysnrltplvgngltvaakvyrsmmt
ylsegsnpedwnipeglyrngefvfkngar

    Sequence, based on observed residues (ATOM records): (download) 
    >2zc6B (B:)
nypaymdnylkevinqveeetgynllttgmdvytnvdqeaqkhlwdiyntdeyvaypdde
lqvastivdvsngkviaqlgarhqssnvsfginqavetnrdwgstmkpitdyapaleygv
ydstativhdepynypgtntpvynwdrgyfgnitlqyalqqsrnvpavetlnkvglnrak
tflnglgidypsihysnaissnttesdkkygassekmaaayaafanggtyykpmyihkvv
fsdgsekefsnvgtramkettaymmtdmmktvlsygtgqnaylawlpqagktgtsnytde
eienhiktsqfvapdelfagytrkysmavwtgysnrltplvgngltvaakvyrsmmtyls
egsnpedwnipeglyrngefvfkn

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2zc6D (D:)
sasnypaymdnylkevinqveeetgynllttgmdvytnvdqeaqkhlwdiyntdeyvayp
ddelqvastivdvsngkviaqlgarhqssnvsfginqavetnrdwgstmkpitdyapale
ygvydstativhdepynypgtntpvynwdrgyfgnitlqyalqqsrnvpavetlnkvgln
raktflnglgidypsihysnaissnttesdkkygassekmaaayaafanggtyykpmyih
kvvfsdgsekefsnvgtramkettaymmtdmmktvlsygtgqnaylawlpqagktgtsny
tdeeienhiktsqfvapdelfagytrkysmavwtgysnrltplvgngltvaakvyrsmmt
ylsegsnpedwnipeglyrngefvfkngar

    Sequence, based on observed residues (ATOM records): (download) 
    >2zc6D (D:)
nypaymdnylkevinqveeetgynllttgmdvytnvdqeaqkhlwdiyntdeyvaypdde
lqvastivdvsngkviaqlgarhqssnvsfginqavetnrdwgstmkpitdyapaleygv
ydstativhdepynypgtntpvynwdrgyfgnitlqyalqqsrnvpavetlnkvglnrak
tflnglgidypsihysnaissnttesdkkygassekmaaayaafanggtyykpmyihkvv
fsdgsekefsnvgtramkettaymmtdmmktvlsygtgqnaylawlpqagktgtsnytde
eienhiktsqfvapdelfagytrkysmavwtgysnrltplvgngltvaakvyrsmmtyls
egsnpedwnipeglyrngefvfkn