PDB entry 2zc3

View 2zc3 on RCSB PDB site
Description: Penicillin-binding protein 2X (PBP 2X) acyl-enzyme complex (biapenem) from Streptococcus pneumoniae
Class: biosynthetic protein
Keywords: PEPTIDOGLYCAN SYNTHESIS, CELL WALL, PENICILLIN-BINDING, ANTIBIOTICS, BIAPENEM, Antibiotic resistance, Cell cycle, Cell division, Cell shape, Cell wall biogenesis/degradation, Membrane, Secreted, Transmembrane, BIOSYNTHETIC PROTEIN
Deposited on 2007-11-02, released 2008-04-08
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.237
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: penicillin-binding protein 2x
    Species: Streptococcus pneumoniae
    Gene: PBPX
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: penicillin-binding protein 2x
    Species: Streptococcus pneumoniae
    Gene: PBPX
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2zc3b_
  • Chain 'C':
    Compound: penicillin-binding protein 2x
    Species: Streptococcus pneumoniae
    Gene: PBPX
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2zc3c1, d2zc3c2
  • Chain 'D':
    Compound: penicillin-binding protein 2x
    Species: Streptococcus pneumoniae
    Gene: PBPX
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: penicillin-binding protein 2x
    Species: Streptococcus pneumoniae
    Gene: PBPX
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2zc3e_
  • Chain 'F':
    Compound: penicillin-binding protein 2x
    Species: Streptococcus pneumoniae
    Gene: PBPX
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2zc3f1, d2zc3f2
  • Heterogens: SO4, BMG, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2zc3B (B:)
lgnivpgteqvsqrtmdgkdvyttissplqsfmetqmdafqekvkgkymtatlvsaktge
ilattqrptfdadtkegitedfvwrdilyqsnyepgstmkvmmlaaaidnntfpggevfn
sselkiadatirdwdvnegltggrmmtfsqgfahssnvgmtlleqkmgdatwldylnrfk
fgvptrfgltdeyagqlpadnivniaqssfgqgisvtqtqmiraftaiandgvmlepkfi
saiydpndqtarksqkeivgnpvskdaasltrtnmvlvgtdpvygtmynhstgkptvtvp
gqnvalksgtaqiadeknggylvgltdyifsavsmspaenpdfilyvtvqqpehysgiql
gefanpilerasamkdslnlqttak

    Sequence, based on observed residues (ATOM records): (download) 
    >2zc3B (B:)
rtmdgkdvyttissplqsfmetqmdafqekvkgkymtatlvsaktgeilattqrptfdad
tkegitedfvwrdilyqsnyepgstmkvmmlaaaidnntfpggevfnsselkiadatird
wdvnegltggrmmtfsqgfahssnvgmtlleqkmgdatwldylnrfkfgvptrfgltdey
agqlpadnivniaqssfgqgisvtqtqmiraftaiandgvmlepkfisaiydpndqtark
sqkeivgnpvskdaasltrtnmvlvgtdpvygtmynhstgkptvtvpgqnvalksgtaqi
adeknggylvgltdyifsavsmspaenpdfilyvtvqqpehysgiqlgefanpilerasa
mkdsln

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2zc3C (C:)
aleqvsqqspypmpsvkdispgdlaeelrrnlvqpivvgtgtkiknssaeegknlapnqq
vlilsdkaeevpdmygwtketaetlakwlnielefqgsgstvqkqdvrantaikdikkit
ltlgd

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2zc3E (E:)
lgnivpgteqvsqrtmdgkdvyttissplqsfmetqmdafqekvkgkymtatlvsaktge
ilattqrptfdadtkegitedfvwrdilyqsnyepgstmkvmmlaaaidnntfpggevfn
sselkiadatirdwdvnegltggrmmtfsqgfahssnvgmtlleqkmgdatwldylnrfk
fgvptrfgltdeyagqlpadnivniaqssfgqgisvtqtqmiraftaiandgvmlepkfi
saiydpndqtarksqkeivgnpvskdaasltrtnmvlvgtdpvygtmynhstgkptvtvp
gqnvalksgtaqiadeknggylvgltdyifsavsmspaenpdfilyvtvqqpehysgiql
gefanpilerasamkdslnlqttak

    Sequence, based on observed residues (ATOM records): (download) 
    >2zc3E (E:)
rtmdgkdvyttissplqsfmetqmdafqekvkgkymtatlvsaktgeilattqrptfdad
tkegitedfvwrdilyqsnyepgstmkvmmlaaaidnntfpggevfnsselkiadatird
wdvnegltggrmmtfsqgfahssnvgmtlleqkmgdatwldylnrfkfgvptrfgltdey
agqlpadnivniaqssfgqgisvtqtqmiraftaiandgvmlepkfisaiydpndqtark
sqkeivgnpvskdaasltrtnmvlvgtdpvygtmynhstgkptvtvpgqnvalksgtaqi
adeknggylvgltdyifsavsmspaenpdfilyvtvqqpehysgiqlgefanpilerasa
mkdslnl

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2zc3F (F:)
aleqvsqqspypmpsvkdispgdlaeelrrnlvqpivvgtgtkiknssaeegknlapnqq
vlilsdkaeevpdmygwtketaetlakwlnielefqgsgstvqkqdvrantaikdikkit
ltlgd