PDB entry 2zbk

View 2zbk on RCSB PDB site
Description: Crystal structure of an intact type II DNA topoisomerase: insights into DNA transfer mechanisms
Deposited on 2007-10-22, released 2008-02-12
The last revision was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3.56 Å
R-factor: 0.313
AEROSPACI score: 0.01 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Type II DNA topoisomerase VI subunit A
    Species: Sulfolobus shibatae [TaxId:2286]
    Gene: top6A
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Type 2 DNA topoisomerase 6 subunit B
    Species: Sulfolobus shibatae [TaxId:2286]
    Gene: top6B
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Type II DNA topoisomerase VI subunit A
    Species: Sulfolobus shibatae [TaxId:2286]
    Gene: top6A
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Type 2 DNA topoisomerase 6 subunit B
    Species: Sulfolobus shibatae [TaxId:2286]
    Gene: top6B
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Type II DNA topoisomerase VI subunit A
    Species: Sulfolobus shibatae [TaxId:2286]
    Gene: top6A
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Type 2 DNA topoisomerase 6 subunit B
    Species: Sulfolobus shibatae [TaxId:2286]
    Gene: top6B
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Type II DNA topoisomerase VI subunit A
    Species: Sulfolobus shibatae [TaxId:2286]
    Gene: top6A
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Type 2 DNA topoisomerase 6 subunit B
    Species: Sulfolobus shibatae [TaxId:2286]
    Gene: top6B
    Database cross-references and differences (RAF-indexed):
  • Heterogens: RDC

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2zbkA (A:)
mssefiskvdkearrkaanilrdkflnlveqlkkgeplvmeipmrtlsnaiydekrklll
lgekklrrnfldlneakrfmqtvlmasiiydalvsdeyptirdlyyrgkhslllksiegn
kivseentwdeqkesdsvivdievftsllreemlilskekgkvvgnlrirsgndvidlsk
tghgayaieptpdlidfidvdaefvlvvekdavfqqlhragfwkqyksilitsagqpdra
trrfvrrlneelklpvyiltdadpygwyifsvfrigsislsyeserlatpdakflgvsmg
difgnsrkkpylseaerknyiikakdadikraeeiknyewfktkawqeeintflqrkakl
eieamaskglkflafqyipekitnkdyia

    Sequence, based on observed residues (ATOM records):
    >2zbkA (A:)
dkearrkaanilrdkflnlveqlkkgeplvmeipmlrrnfldlneakrfmqtvlmasiiy
dalvsdeyptirdlyyrgkhslllksieentwdeqkesdsvivdievftsllreemlils
kekgkvvgnlrirsgndvidlsktghgayaieptpdlidfidvdaefvlvvekdavfqql
hragfwkqyksilitsagqpdratrrfvrrlneelklpvyiltdadpygwyifsvfrigs
iserlatpdakflgvsmgdifgnsrkkpylseaerknyiikakdadikraeeiknyewfk
tkawqeeintflqrkakleieamaskglkflafqyipekitnkdyia

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2zbkB (B:)
msakekftslspaeffkrnpelagfpnparalyqtvreliensldatdvhgilpnikiti
dliddarqiykvnvvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavlysq
mhqdkpieietspvnskriytfklkidinknepiivergsventrgfhgtsvaisipgdw
pkaksriyeyikrtyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdree
ikilinnlkrdytikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlvetf
kkdedfrspsadslsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvafgg
sipvgeepivlryankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcstki
pyksagkesiaeveniekeiknalmevarklkqylsekrkeqeakkkllaylkyipevsr
slatflasgnkelvskyqneiseglfkliskkldlinieeyrkvyrvdse

    Sequence, based on observed residues (ATOM records):
    >2zbkB (B:)
effkrnpelagfpnparalyqtvreliensldatdvhgilpnikitidliddarqiykvn
vvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavlysqmhqdkpieietsp
vnskriytfklkidinknepiivergsventrgfhgtsvaisipgdwpkaksriyeyikr
tyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdreeikilinnlkrdyt
ikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlvetfkkdedfrspsads
lsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvafggsipvgeepivlry
ankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcstkipyksagkesiaev
eniekeiknalmevarklkqylsekrkeqeakkkllaylkyipevsrslatflasgnkel
vskyqneiseglfkliskkldlinie

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2zbkC (C:)
mssefiskvdkearrkaanilrdkflnlveqlkkgeplvmeipmrtlsnaiydekrklll
lgekklrrnfldlneakrfmqtvlmasiiydalvsdeyptirdlyyrgkhslllksiegn
kivseentwdeqkesdsvivdievftsllreemlilskekgkvvgnlrirsgndvidlsk
tghgayaieptpdlidfidvdaefvlvvekdavfqqlhragfwkqyksilitsagqpdra
trrfvrrlneelklpvyiltdadpygwyifsvfrigsislsyeserlatpdakflgvsmg
difgnsrkkpylseaerknyiikakdadikraeeiknyewfktkawqeeintflqrkakl
eieamaskglkflafqyipekitnkdyia

    Sequence, based on observed residues (ATOM records):
    >2zbkC (C:)
dkearrkaanilrdkflnlveqlkkgeplvmeipmlrrnfldlneakrfmqtvlmasiiy
dalvsdeyptirdlyyrgkhslllksieentwdeqkesdsvivdievftsllreemlils
kekgkvvgnlrirsgndvidlsktghgayaieptpdlidfidvdaefvlvvekdavfqql
hragfwkqyksilitsagqpdratrrfvrrlneelklpvyiltdadpygwyifsvfrigs
iserlatpdakflgvsmgdifgnsrkkpylseaerknyiikakdadikraeeiknyewfk
tkawqeeintflqrkakleieamaskglkflafqyipekitnkdyia

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2zbkD (D:)
msakekftslspaeffkrnpelagfpnparalyqtvreliensldatdvhgilpnikiti
dliddarqiykvnvvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavlysq
mhqdkpieietspvnskriytfklkidinknepiivergsventrgfhgtsvaisipgdw
pkaksriyeyikrtyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdree
ikilinnlkrdytikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlvetf
kkdedfrspsadslsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvafgg
sipvgeepivlryankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcstki
pyksagkesiaeveniekeiknalmevarklkqylsekrkeqeakkkllaylkyipevsr
slatflasgnkelvskyqneiseglfkliskkldlinieeyrkvyrvdse

    Sequence, based on observed residues (ATOM records):
    >2zbkD (D:)
effkrnpelagfpnparalyqtvreliensldatdvhgilpnikitidliddarqiykvn
vvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavlysqmhqdkpieietsp
vnskriytfklkidinknepiivergsventrgfhgtsvaisipgdwpkaksriyeyikr
tyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdreeikilinnlkrdyt
ikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlvetfkkdedfrspsads
lsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvafggsipvgeepivlry
ankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcstkipyksagkesiaev
eniekeiknalmevarklkqylsekrkeqeakkkllaylkyipevsrslatflasgnkel
vskyqneiseglfkliskkldlinie

  • Chain 'E':
    Sequence, based on SEQRES records:
    >2zbkE (E:)
mssefiskvdkearrkaanilrdkflnlveqlkkgeplvmeipmrtlsnaiydekrklll
lgekklrrnfldlneakrfmqtvlmasiiydalvsdeyptirdlyyrgkhslllksiegn
kivseentwdeqkesdsvivdievftsllreemlilskekgkvvgnlrirsgndvidlsk
tghgayaieptpdlidfidvdaefvlvvekdavfqqlhragfwkqyksilitsagqpdra
trrfvrrlneelklpvyiltdadpygwyifsvfrigsislsyeserlatpdakflgvsmg
difgnsrkkpylseaerknyiikakdadikraeeiknyewfktkawqeeintflqrkakl
eieamaskglkflafqyipekitnkdyia

    Sequence, based on observed residues (ATOM records):
    >2zbkE (E:)
dkearrkaanilrdkflnlveqlkkgeplvmeipmlrrnfldlneakrfmqtvlmasiiy
dalvsdeyptirdlyyrgkhslllksieentwdeqkesdsvivdievftsllreemlils
kekgkvvgnlrirsgndvidlsktghgayaieptpdlidfidvdaefvlvvekdavfqql
hragfwkqyksilitsagqpdratrrfvrrlneelklpvyiltdadpygwyifsvfrigs
iserlatpdakflgvsmgdifgnsrkkpylseaerknyiikakdadikraeeiknyewfk
tkawqeeintflqrkakleieamaskglkflafqyipekitnkdyia

  • Chain 'F':
    Sequence, based on SEQRES records:
    >2zbkF (F:)
msakekftslspaeffkrnpelagfpnparalyqtvreliensldatdvhgilpnikiti
dliddarqiykvnvvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavlysq
mhqdkpieietspvnskriytfklkidinknepiivergsventrgfhgtsvaisipgdw
pkaksriyeyikrtyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdree
ikilinnlkrdytikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlvetf
kkdedfrspsadslsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvafgg
sipvgeepivlryankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcstki
pyksagkesiaeveniekeiknalmevarklkqylsekrkeqeakkkllaylkyipevsr
slatflasgnkelvskyqneiseglfkliskkldlinieeyrkvyrvdse

    Sequence, based on observed residues (ATOM records):
    >2zbkF (F:)
effkrnpelagfpnparalyqtvreliensldatdvhgilpnikitidliddarqiykvn
vvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavlysqmhqdkpieietsp
vnskriytfklkidinknepiivergsventrgfhgtsvaisipgdwpkaksriyeyikr
tyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdreeikilinnlkrdyt
ikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlvetfkkdedfrspsads
lsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvafggsipvgeepivlry
ankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcstkipyksagkesiaev
eniekeiknalmevarklkqylsekrkeqeakkkllaylkyipevsrslatflasgnkel
vskyqneiseglfkliskkldlinie

  • Chain 'G':
    Sequence, based on SEQRES records:
    >2zbkG (G:)
mssefiskvdkearrkaanilrdkflnlveqlkkgeplvmeipmrtlsnaiydekrklll
lgekklrrnfldlneakrfmqtvlmasiiydalvsdeyptirdlyyrgkhslllksiegn
kivseentwdeqkesdsvivdievftsllreemlilskekgkvvgnlrirsgndvidlsk
tghgayaieptpdlidfidvdaefvlvvekdavfqqlhragfwkqyksilitsagqpdra
trrfvrrlneelklpvyiltdadpygwyifsvfrigsislsyeserlatpdakflgvsmg
difgnsrkkpylseaerknyiikakdadikraeeiknyewfktkawqeeintflqrkakl
eieamaskglkflafqyipekitnkdyia

    Sequence, based on observed residues (ATOM records):
    >2zbkG (G:)
dkearrkaanilrdkflnlveqlkkgeplvmeipmlrrnfldlneakrfmqtvlmasiiy
dalvsdeyptirdlyyrgkhslllksieentwdeqkesdsvivdievftsllreemlils
kekgkvvgnlrirsgndvidlsktghgayaieptpdlidfidvdaefvlvvekdavfqql
hragfwkqyksilitsagqpdratrrfvrrlneelklpvyiltdadpygwyifsvfrigs
iserlatpdakflgvsmgdifgnsrkkpylseaerknyiikakdadikraeeiknyewfk
tkawqeeintflqrkakleieamaskglkflafqyipekitnkdyia

  • Chain 'H':
    Sequence, based on SEQRES records:
    >2zbkH (H:)
msakekftslspaeffkrnpelagfpnparalyqtvreliensldatdvhgilpnikiti
dliddarqiykvnvvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavlysq
mhqdkpieietspvnskriytfklkidinknepiivergsventrgfhgtsvaisipgdw
pkaksriyeyikrtyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdree
ikilinnlkrdytikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlvetf
kkdedfrspsadslsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvafgg
sipvgeepivlryankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcstki
pyksagkesiaeveniekeiknalmevarklkqylsekrkeqeakkkllaylkyipevsr
slatflasgnkelvskyqneiseglfkliskkldlinieeyrkvyrvdse

    Sequence, based on observed residues (ATOM records):
    >2zbkH (H:)
effkrnpelagfpnparalyqtvreliensldatdvhgilpnikitidliddarqiykvn
vvdngigippqevpnafgrvlysskyvnrqtrgmyglgvkaavlysqmhqdkpieietsp
vnskriytfklkidinknepiivergsventrgfhgtsvaisipgdwpkaksriyeyikr
tyiitpyaefifkdpegnvtyyprltnkipkppqevkphpygvdreeikilinnlkrdyt
ikeflvnefqsigdttadkilelaglkpnkkvknlteeeitrlvetfkkdedfrspsads
lsvigedlielglkkifnpdfaasitrkpkayqghpfiveagvafggsipvgeepivlry
ankipliydeksdviwkvveeldwkrygiesdqyqmvvmvhlcstkipyksagkesiaev
eniekeiknalmevarklkqylsekrkeqeakkkllaylkyipevsrslatflasgnkel
vskyqneiseglfkliskkldlinie