PDB entry 2z80

View 2z80 on RCSB PDB site
Description: crystal structure of the tlr1-tlr2 heterodimer induced by binding of a tri-acylated lipopeptide
Deposited on 2007-08-30, released 2007-09-25
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Toll-like receptor 2, Variable lymphocyte receptor B
    Species: , [TaxId:7764]
    Gene: TLR2, TIL4, VLRB
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60603 (Start-283)
      • linker (284-288)
    • Uniprot Q4G1L2 (289-352)
  • Chain 'B':
    Compound: Toll-like receptor 2, Variable lymphocyte receptor B
    Species: , [TaxId:7764]
    Gene: TLR2, TIL4, VLRB
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60603 (Start-283)
      • linker (284-288)
    • Uniprot Q4G1L2 (289-352)
  • Heterogens: NAG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2z80A (A:)
mphtlwmvwvlgviislskeessnqaslscdrngickgssgslnsipsglteavksldls
nnrityisnsdlqrcvnlqalvltsngintieedsfsslgslehldlsynylsnlssswf
kplssltflnllgnpyktlgetslfshltklqilrvgnmdtftkiqrkdfagltfleele
idasdlqsyepkslksiqnvshlilhmkqhillleifvdvtssveclelrdtdldtfhfs
elstgetnslikkftfrnvkitdeslfqvmkllnqisgllelefsrnqlksvpdgifdrl
tslqkiwlhtnpwdcscpridylsrwlnknsqkeqgsakcsgsgkpvrsiicp

    Sequence, based on observed residues (ATOM records):
    >2z80A (A:)
slscdrngickgssgslnsipsglteavksldlsnnrityisnsdlqrcvnlqalvltsn
gintieedsfsslgslehldlsynylsnlssswfkplssltflnllgnpyktlgetslfs
hltklqilrvgnmdtftkiqrkdfagltfleeleidasdlqsyepkslksiqnvshlilh
mkqhillleifvdvtssveclelrdtdldtfhfstnslikkftfrnvkitdeslfqvmkl
lnqisgllelefsrnqlksvpdgifdrltslqkiwlhtnpwdcscpridylsrwlnknsq
keqgsakcsgsgkpvrsiicp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2z80B (B:)
mphtlwmvwvlgviislskeessnqaslscdrngickgssgslnsipsglteavksldls
nnrityisnsdlqrcvnlqalvltsngintieedsfsslgslehldlsynylsnlssswf
kplssltflnllgnpyktlgetslfshltklqilrvgnmdtftkiqrkdfagltfleele
idasdlqsyepkslksiqnvshlilhmkqhillleifvdvtssveclelrdtdldtfhfs
elstgetnslikkftfrnvkitdeslfqvmkllnqisgllelefsrnqlksvpdgifdrl
tslqkiwlhtnpwdcscpridylsrwlnknsqkeqgsakcsgsgkpvrsiicp

    Sequence, based on observed residues (ATOM records):
    >2z80B (B:)
slscdrngickgssgslnsipsglteavksldlsnnrityisnsdlqrcvnlqalvltsn
gintieedsfsslgslehldlsynylsnlssswfkplssltflnllgnpyktlgetslfs
hltklqilrvgnmdtftkiqrkdfagltfleeleidasdlqsyepkslksiqnvshlilh
mkqhillleifvdvtssveclelrdtdldtfhfsnslikkftfrnvkitdeslfqvmkll
nqisgllelefsrnqlksvpdgifdrltslqkiwlhtnpwdcscpridylsrwlnknsqk
eqgsakcsgsgkpvrsiicp