PDB entry 2z7s

View 2z7s on RCSB PDB site
Description: Crystal Structure of the N-terminal Kinase Domain of Human RSK1 bound to Purvalnol A
Class: transferase
Keywords: protein kinase, cancer, kinase inhibitor, TRANSFERASE
Deposited on 2007-08-28, released 2008-05-13
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.279
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ribosomal protein S6 kinase alpha-1
    Species: Homo sapiens [TaxId:9606]
    Gene: RPS6KA1, RSK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2z7sa_
  • Heterogens: P01, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2z7sA (A:)
qpskdegvlkeisithhvkagsekadpshfellkvlgqgsfgkvflvrkvtrpdsghlya
mkvlkkatlkvrdrvrtkmerdiladvnhpfvvklhyafqtegklylildflrggdlftr
lskevmfteedvkfylaelalgldhlhslgiiyrdlkpenilldeeghikltdfglskea
idhekkaysfcgtveymapevvnrqghshsadwwsygvlmfemltgslpfqgkdrketmt
lilkaklgmpqflsteaqsllralfkrnpanrlgsgpdgaeeikrhvfystidwnklyrr
eikppfkpavaqpddtfyfdt

    Sequence, based on observed residues (ATOM records): (download) 
    >2z7sA (A:)
kadpshfellkvlgqgsfgkvflvrkvtrpdsghlyamkvlkiladvnhpfvvklhyafq
tegklylildflrggdlftrlskevmfteedvkfylaelalgldhlhslgiiyrdlkpen
illdeeghikltdfglskegtveymapevvnrqghshsadwwsygvlmfemltgslpfqg
kdrketmtlilkaklgmpqflsteaqsllralfkrnpanrlgsgpdgaeeikrhvfysti
dwnklyrreikppfkp