PDB entry 2z7q

View 2z7q on RCSB PDB site
Description: Crystal structure of the N-terminal kinase domain of human RSK-1 bound to AMP-PCP
Class: transferase
Keywords: protein kinase; cancer; kinase inhibitor, ATP-binding, Magnesium, Metal-binding, Nucleotide-binding, Phosphorylation, Serine/threonine-protein kinase, Transferase
Deposited on 2007-08-28, released 2008-05-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-02-15, with a file datestamp of 2012-02-10.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.264
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ribosomal protein S6 kinase alpha-1
    Species: Homo sapiens [TaxId:9606]
    Gene: RPS6KA1, RSK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z7qa_
  • Heterogens: MG, ACP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2z7qA (A:)
qpskdegvlkeisithhvkagsekadpshfellkvlgqgsfgkvflvrkvtrpdsghlya
mkvlkkatlkvrdrvrtkmerdiladvnhpfvvklhyafqtegklylildflrggdlftr
lskevmfteedvkfylaelalgldhlhslgiiyrdlkpenilldeeghikltdfglskea
idhekkaysfcgtveymapevvnrqghshsadwwsygvlmfemltgslpfqgkdrketmt
lilkaklgmpqflsteaqsllralfkrnpanrlgsgpdgaeeikrhvfystidwnklyrr
eikppfkpavaqpddtfyfdt

    Sequence, based on observed residues (ATOM records): (download) 
    >2z7qA (A:)
kadpshfellkvlgqgsfgkvflvrkvtrpdsghlyamkvliladvnhpfvvklhyafqt
egklylildflrggdlftrlskevmfteedvkfylaelalgldhlhslgiiyrdlkpeni
lldeeghikltdfglskegtveymapevvnrqghshsadwwsygvlmfemltgslpfqgk
drketmtlilkaklgmpqflsteaqsllralfkrnpanrlgsgpdgaeeikrhvfystid
wnklyrreikppfkp