PDB entry 2z5s

View 2z5s on RCSB PDB site
Description: molecular basis for the inhibition of p53 by mdmx
Deposited on 2007-07-17, released 2007-11-06
The last revision was dated 2019-11-06, with a file datestamp of 2019-11-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'M':
    Compound: mdm4 protein
    Species: Danio rerio [TaxId:7955]
    Gene: MDM4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q4V944 (14-End)
      • expression tag (12-13)
  • Chain 'N':
    Compound: mdm4 protein
    Species: Danio rerio [TaxId:7955]
    Gene: MDM4
    Database cross-references and differences (RAF-indexed):
  • Chain 'O':
    Compound: mdm4 protein
    Species: Danio rerio [TaxId:7955]
    Gene: MDM4
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: Cellular tumor antigen p53
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'Q':
    Compound: Cellular tumor antigen p53
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'R':
    Compound: Cellular tumor antigen p53
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'M':
    Sequence, based on SEQRES records:
    >2z5sM (M:)
mahhhhhhddddkirtlpgegtqvhprapllqilkvagaqeevftlkevmhylgqyimmk
qlydkqrqhivhchddplgellevgsfsvknpspvyemlkrnlvilnnsdaaknlsvgkd
snespsedpgqvssgsinsa

    Sequence, based on observed residues (ATOM records):
    >2z5sM (M:)
kirtlegtqvhprapllqilkvagaqeevftlkevmhylgqyimmkqlydkqrqhivhch
ddplgellevgsfsvknpspvyemlkrnlvil

  • Chain 'N':
    Sequence, based on SEQRES records:
    >2z5sN (N:)
mahhhhhhddddkirtlpgegtqvhprapllqilkvagaqeevftlkevmhylgqyimmk
qlydkqrqhivhchddplgellevgsfsvknpspvyemlkrnlvilnnsdaaknlsvgkd
snespsedpgqvssgsinsa

    Sequence, based on observed residues (ATOM records):
    >2z5sN (N:)
tqvhprapllqilkvagaqeevftlkevmhylgqyimmkqlydkqrqhivhchddplgel
levgsfsvknpspvyemlkrnlviln

  • Chain 'O':
    Sequence, based on SEQRES records:
    >2z5sO (O:)
mahhhhhhddddkirtlpgegtqvhprapllqilkvagaqeevftlkevmhylgqyimmk
qlydkqrqhivhchddplgellevgsfsvknpspvyemlkrnlvilnnsdaaknlsvgkd
snespsedpgqvssgsinsa

    Sequence, based on observed residues (ATOM records):
    >2z5sO (O:)
gtqvhprapllqilkvagaqeevftlkevmhylgqyimmkqlydkqrqhivhchddplge
llevgsfsvknpspvyemlkrnlvil

  • Chain 'P':
    Sequence, based on SEQRES records:
    >2z5sP (P:)
sqetfsdlwkllpen

    Sequence, based on observed residues (ATOM records):
    >2z5sP (P:)
etfsdlwkllp

  • Chain 'Q':
    Sequence, based on SEQRES records:
    >2z5sQ (Q:)
sqetfsdlwkllpen

    Sequence, based on observed residues (ATOM records):
    >2z5sQ (Q:)
etfsdlwkllp

  • Chain 'R':
    Sequence, based on SEQRES records:
    >2z5sR (R:)
sqetfsdlwkllpen

    Sequence, based on observed residues (ATOM records):
    >2z5sR (R:)
tfsdlwkllp