PDB entry 2z4k

View 2z4k on RCSB PDB site
Description: Crystal structure of the bacterial ribosome from Escherichia coli in complex with paromomycin and ribosome recycling factor (RRF). This file contains the 30S subunit of the first 70S ribosome, with paromomycin bound. The entire crystal structure contains two 70S ribosomes and is described in remark 400.
Class: ribosome
Keywords: RNA-protein complex, RIBOSOME
Deposited on 2007-06-19, released 2007-09-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-12-10, with a file datestamp of 2014-12-05.
Experiment type: XRAY
Resolution: 4.45 Å
R-factor: 0.263
AEROSPACI score: -0.01 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 16s rRNA
    Species: Escherichia coli [TaxId:562]
  • Chain 'B':
    Compound: 30S ribosomal protein S2
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z4kb1
  • Chain 'C':
    Compound: 30S ribosomal protein S3
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z4kc1, d2z4kc2
  • Chain 'D':
    Compound: 30S ribosomal protein S4
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z4kd1
  • Chain 'E':
    Compound: 30S ribosomal protein S5
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z4ke1, d2z4ke2
  • Chain 'F':
    Compound: 30S ribosomal protein S6
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z4kf1
  • Chain 'G':
    Compound: 30S ribosomal protein S7
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z4kg1
  • Chain 'H':
    Compound: 30S ribosomal protein S8
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z4kh1
  • Chain 'I':
    Compound: 30S ribosomal protein S9
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z4ki1
  • Chain 'J':
    Compound: 30S ribosomal protein S10
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z4kj1
  • Chain 'K':
    Compound: 30S ribosomal protein S11
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z4kk1
  • Chain 'L':
    Compound: 30S ribosomal protein S12
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z4kl1
  • Chain 'M':
    Compound: 30S ribosomal protein S13
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z4km1
  • Chain 'N':
    Compound: 30S ribosomal protein S14
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z4kn1
  • Chain 'O':
    Compound: 30S ribosomal protein S15
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: 30S ribosomal protein S16
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z4kp1
  • Chain 'Q':
    Compound: 30S ribosomal protein S17
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z4kq1
  • Chain 'R':
    Compound: 30S ribosomal protein S18
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z4kr1
  • Chain 'S':
    Compound: 30S ribosomal protein S19
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z4ks1
  • Chain 'T':
    Compound: 30S ribosomal protein S20
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z4kt1
  • Chain 'U':
    Compound: 30S ribosomal protein S21
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2z4ku1
  • Heterogens: MG, PAR, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2z4kB (B:)
atvsmrdmlkagvhfghqtrywnpkmkpfifgarnkvhiinlektvpmfnealaelnkia
srkgkilfvgtkraaseavkdaalscdqffvnhrwlggmltnwktvrqsikrlkdletqs
qdgtfdkltkkealmrtreleklenslggikdmgglpdalfvidadhehiaikeannlgi
pvfaivdtnsdpdgvdfvipgnddairavtlylgavaatvregrsqdlasqaeesfveae

    Sequence, based on observed residues (ATOM records): (download) 
    >2z4kB (B:)
mlkagvhfghqtrywnpkmkpfifgarnkvhiinlektvpmfnealaelnkiasrkgkil
fvgtkraaseavkdaalscdqffvnhrwlggmltnwktvrqsikrlkdletqsqdgtfdk
ltkkealmrtreleklenslggikdmgglpdalfvidadhehiaikeannlgipvfaivd
tnsdpdgvdfvipgnddairavtlylgavaatvregrs

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2z4kC (C:)
gqkvhpngirlgivkpwnstwfantkefadnldsdfkvrqyltkelakasvsrivierpa
ksirvtihtarpgivigkkgedveklrkvvadiagvpaqiniaevrkpeldaklvadsit
sqlerrvmfrramkravqnamrlgakgikvevsgrlggaeiartewyregrvplhtlrad
idyntseahttygvigvkvwifkgeilggmaaveqpekpaaqpkkqqrkgrk

    Sequence, based on observed residues (ATOM records): (download) 
    >2z4kC (C:)
gqkvhpngirlgivkpwnstwfantkefadnldsdfkvrqyltkelakasvsrivierpa
ksirvtihtarpgivigkkgedveklrkvvadiagvpaqiniaevrkpeldaklvadsit
sqlerrvmfrramkravqnamrlgakgikvevsgrlggaeiartewyregrvplhtlrad
idyntseahttygvigvkvwifkgei

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2z4kD (D:)
arylgpklklsrregtdlflksgvraidtkckieqapgqhgarkprlsdygvqlrekqkv
rriygvlerqfrnyykeaarlkgntgenllallegrldnvvyrmgfgatraearqlvshk
aimvngrvvniasyqvspndvvsirekakkqsrvkaalelaeqrekptwlevdagkmegt
fkrkpersdlsadinehlivelysk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2z4kE (E:)
ahiekqagelqekliavnrvsktvkggrifsftaltvvgdgngrvgfgygkarevpaaiq
kamekarrnminvalnngtlqhpvkgvhtgsrvfmqpasegtgiiaggamravlevagvh
nvlakaygstnpinvvratidglenmnspemvaakrgksveeilgk

    Sequence, based on observed residues (ATOM records): (download) 
    >2z4kE (E:)
elqekliavnrvsktvkggrifsftaltvvgdgngrvgfgygkarevpaaiqkamekarr
nminvalnngtlqhpvkgvhtgsrvfmqpasegtgiiaggamravlevagvhnvlakayg
stnpinvvratidglenmnspemvaakrgk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2z4kF (F:)
mrhyeivfmvhpdqseqvpgmierytaaitgaegkihrledwgrrqlaypinklhkahyv
lmnveapqevidelettfrfndavirsmvmrtkhavteaspmvkakderrerrddfanet
addaeagdseeeeee

    Sequence, based on observed residues (ATOM records): (download) 
    >2z4kF (F:)
mrhyeivfmvhpdqseqvpgmierytaaitgaegkihrledwgrrqlaypinklhkahyv
lmnveapqevidelettfrfndavirsmvmrtkhavteas

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2z4kG (G:)
prrrvigqrkilpdpkfgsellakfvnilmvdgkkstaesivysaletlaqrsgkselea
fevalenvrptvevksrrvggstyqvpvevrpvrrnalamrwiveaarkrgdksmalrla
nelsdaaenkgtavkkredvhrmaeankafahyrwlslrsfshqagasskqpalgyln

    Sequence, based on observed residues (ATOM records): (download) 
    >2z4kG (G:)
rrrvigqrkilpdpkfgsellakfvnilmvdgkkstaesivysaletlaqrsgkseleaf
evalenvrptvevksrrvggstyqvpvevrpvrrnalamrwiveaarkrgdksmalrlan
elsdaaenkgtavkkredvhrmaeankafa

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2z4kH (H:)
smqdpiadmltrirngqaankaavtmpssklkvaianvlkeegfiedfkvegdtkpelel
tlkyfqgkavvesiqrvsrpglriykrkdelpkvmaglgiavvstskgvmtdraarqagl
ggeiicyva

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >2z4kI (I:)
aenqyygtgrrkssaarvfikpgngkivinqrsleqyfgretarmvvrqplelvdmvekl
dlyitvkgggisgqagairhgitralmeydeslrselrkagfvtrdarqverkkvglrka
rrrpqfskr

    Sequence, based on observed residues (ATOM records): (download) 
    >2z4kI (I:)
nqyygtgrrkssaarvfikpgngkivinqrsleqyfgretarmvvrqplelvdmvekldl
yitvkgggisgqagairhgitralmeydeslrselrkagfvtrdarqverkkvglrkarr
rpqfskr

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >2z4kJ (J:)
mqnqririrlkafdhrlidqataeivetakrtgaqvrgpiplptrkerftvlisphvnkd
ardqyeirthlrlvdiveptektvdalmrldlaagvdvqislg

    Sequence, based on observed residues (ATOM records): (download) 
    >2z4kJ (J:)
ririrlkafdhrlidqataeivetakrtgaqvrgpiplptrkerftvlisphvnkdardq
yeirthlrlvdiveptektvdalmrldlaagvdvqisl

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >2z4kK (K:)
akapirarkrvrkqvsdgvahihasfnntivtitdrqgnalgwataggsgfrgsrkstpf
aaqvaaercadavkeygiknlevmvkgpgpgrestiralnaagfritnitdvtpiphngc
rppkkrrv

    Sequence, based on observed residues (ATOM records): (download) 
    >2z4kK (K:)
rkqvsdgvahihasfnntivtitdrqgnalgwataggsgfrgsrkstpfaaqvaaercad
avkeygiknlevmvkgpgpgrestiralnaagfritnitdvtpiphngcrppkkrrv

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2z4kL (L:)
atvnqlvrkprarkvaksnvpaleacpqkrgvctrvytttpkkpnsalrkvcrvrltngf
evtsyiggeghnlqehsvilirggrvkdlpgvryhtvrgaldcsgvkdrkqarskygvkr
pka

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >2z4kM (M:)
ariaginipdhkhavialtsiygvgktrskailaaagiaedvkiselsegqidtlrdeva
kfvvegdlrreismsikrlmdlgcyrglrhrrglpvrgqrtktnartrkgprkpikk

    Sequence, based on observed residues (ATOM records): (download) 
    >2z4kM (M:)
ariaginipdhkhavialtsiygvgktrskailaaagiaedvkiselsegqidtlrdeva
kfvvegdlrreismsikrlmdlgcyrglrhrrglpvrgqrtktnartrkgprkp

  • Chain 'N':
    Sequence, based on SEQRES records: (download) 
    >2z4kN (N:)
akqsmkarevkrvaladkyfakraelkaiisdvnasdedrwnavlklqtlprdsspsrqr
nrcrqtgrphgflrkfglsrikvreaamrgeipglkkasw

    Sequence, based on observed residues (ATOM records): (download) 
    >2z4kN (N:)
akqsmkarevkrvaladkyfakraelkaiisdvnarwnavlklqtlprdsspsrqrnrcr
qtgrphgflrkfglsrikvreaamrgeipglkkasw

  • Chain 'O':
    No sequence available.

  • Chain 'P':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2z4kP (P:)
mvtirlarhgakkrpfyqvvvadsrnarngrfiervgffnpiasekeegtrldldriahw
vgqgatisdrvaalikevnkaa

  • Chain 'Q':
    Sequence, based on SEQRES records: (download) 
    >2z4kQ (Q:)
tdkirtlqgrvvsdkmeksivvaierfvkhpiygkfikrttklhvhdennecgigdvvei
recrplsktkswtlvrvvekavl

    Sequence, based on observed residues (ATOM records): (download) 
    >2z4kQ (Q:)
kirtlqgrvvsdkmeksivvaierfvkhpiygkfikrttklhvhdennecgigdvveire
crplsktkswtlvrvvekav

  • Chain 'R':
    Sequence, based on SEQRES records: (download) 
    >2z4kR (R:)
aryfrrrkfcrftaegvqeidykdiatlknyitesgkivpsritgtrakyqrqlaraikr
arylsllpytdrhq

    Sequence, based on observed residues (ATOM records): (download) 
    >2z4kR (R:)
eidykdiatlknyitesgkivpsritgtrakyqrqlaraikrarylsllpytdrh

  • Chain 'S':
    Sequence, based on SEQRES records: (download) 
    >2z4kS (S:)
prslkkgpfidlhllkkvekavesgdkkplrtwsrrstifpnmigltiavhngrqhvpvf
vtdemvghklgefaptrtyrghaadkkakkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2z4kS (S:)
rslkkgpfidlhllkkvekavesgdkkplrtwsrrstifpnmigltiavhngrqhvpvfv
tdemvghklgefaptrtyr

  • Chain 'T':
    Sequence, based on SEQRES records: (download) 
    >2z4kT (T:)
aniksakkraiqsekarkhnasrrsmmrtfikkvyaaieagdkaaaqkafnemqpivdrq
aakglihknkaarhkanltaqinkla

    Sequence, based on observed residues (ATOM records): (download) 
    >2z4kT (T:)
niksakkraiqsekarkhnasrrsmmrtfikkvyaaieagdkaaaqkafnemqpivdrqa
akglihknkaarhkanltaqinkla

  • Chain 'U':
    Sequence, based on SEQRES records: (download) 
    >2z4kU (U:)
pvikvrenepfdvalrrfkrscekagvlaevrrrefyekptterkrakasavkrhakkla
renarrtrly

    Sequence, based on observed residues (ATOM records): (download) 
    >2z4kU (U:)
ikvrenepfdvalrrfkrscekagvlaevrrrefyekptterkrakasavk