PDB entry 2z3e

View 2z3e on RCSB PDB site
Description: A Mechanistic view of Enzyme Inhibition and Peptide Hydrolysis in the Active Site of the SARS-CoV 3C-Like peptidase
Class: hydrolase/hydrolase inhibitor
Keywords: SARS, 3C-like peptidase, 3CL, main proteinase, viral cysteine protease, HYDROLASE-HYDROLASE INHIBITOR COMPLEX, VIRAL PROTEIN
Deposited on 2007-06-04, released 2007-07-03
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.32 Å
R-factor: 0.19
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Replicase polyprotein 1ab (pp1ab)
    Species: SARS coronavirus [TaxId:227859]
    Gene: rep
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2z3ea_
  • Chain 'I':
    Compound: ACE VAL Z3E LEU KCQ peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2Z3E (Start-3)
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2z3eA (A:)
sgfrkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedllir
ksnhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacyng
spsgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegk
fygpfvdrqtaqaagtdttitlnvlawlyaavingdrwflnrftttlndfnlvamkynye
pltqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvrqc
sgvtfq

  • Chain 'I':
    No sequence available.