PDB entry 2z2p

View 2z2p on RCSB PDB site
Description: crystal structure of catalytically inactive h270a virginiamycin b lyase from staphylococcus aureus with quinupristin
Deposited on 2007-05-25, released 2007-06-19
The last revision was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: virginiamycin B lyase
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: vgb, vgh
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q53744
      • see remark 999 (50)
      • see remark 999 (53-55)
      • see remark 999 (210-211)
      • engineered mutation (269)
  • Chain 'B':
    Compound: virginiamycin B lyase
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: vgb, vgh
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q53744
      • see remark 999 (50)
      • see remark 999 (53-55)
      • see remark 999 (210-211)
      • engineered mutation (269)
  • Chain 'C':
    Compound: quinupristin
    Species: STREPTOMYCES GRAMINOFACIEN, synthetic [TaxId:68212]
    Database cross-references and differences (RAF-indexed):
    • PDB 2Z2P (0-6)
  • Chain 'D':
    Compound: quinupristin
    Species: STREPTOMYCES GRAMINOFACIEN, synthetic [TaxId:68212]
    Database cross-references and differences (RAF-indexed):
    • PDB 2Z2P (0-6)
  • Heterogens: MG, DOL, MHT

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2z2pA (A:)
mefklqelnltnqdtgpygitvsdkgkvwitqhkanmiscinldgkiteyelpnkgakvm
cltissdgevwftenaankigritkkgiikeytlpnpdsapygitegpngdiwftemngn
rigritddgkireyelpnkgsypsfitlgsdnalwftenqnnaigritesgditefkipt
pasgpvgitkgnddalwfveiignkigrittsgeitefkiptpnarphaitagagidlwf
tewgankigrltsnniieeypiqiksaepagicfdgetiwfamecdkigkltlikdnme

    Sequence, based on observed residues (ATOM records):
    >2z2pA (A:)
efklqelnltnqdtgpygitvsdkgkvwitqhkanmiscinldgkiteyelpnkgakvmc
ltissdgevwftenaankigritkkgiikeytlpnpdsapygitegpngdiwftemngnr
igritddgkireyelpnkgsypsfitlgsdnalwftenqnnaigritesgditefkiptp
asgpvgitkgnddalwfveiignkigrittsgeitefkiptpnarphaitagagidlwft
ewgankigrltsnniieeypiqiksaepagicfdgetiwfamecdkigkltli

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2z2pB (B:)
mefklqelnltnqdtgpygitvsdkgkvwitqhkanmiscinldgkiteyelpnkgakvm
cltissdgevwftenaankigritkkgiikeytlpnpdsapygitegpngdiwftemngn
rigritddgkireyelpnkgsypsfitlgsdnalwftenqnnaigritesgditefkipt
pasgpvgitkgnddalwfveiignkigrittsgeitefkiptpnarphaitagagidlwf
tewgankigrltsnniieeypiqiksaepagicfdgetiwfamecdkigkltlikdnme

    Sequence, based on observed residues (ATOM records):
    >2z2pB (B:)
efklqelnltnqdtgpygitvsdkgkvwitqhkanmiscinldgkiteyelpnkgakvmc
ltissdgevwftenaankigritkkgiikeytlpnpdsapygitegpngdiwftemngnr
igritddgkireyelpnkgsypsfitlgsdnalwftenqnnaigritesgditefkiptp
asgpvgitkgnddalwfveiignkigrittsgeitefkiptpnarphaitagagidlwft
ewgankigrltsnniieeypiqiksaepagicfdgetiwfamecdkigkltli

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >2z2pC (C:)
xtxpxxx

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >2z2pD (D:)
xtxpxxx