PDB entry 2yyn

View 2yyn on RCSB PDB site
Description: Crystal structure of human bromodomain protein
Class: transcription
Keywords: bromo domain, TRANSCRIPTION, Structural Genomics, NPPSFA, National Project on Protein Structural and Functional Analyses, RIKEN Structural Genomics/Proteomics Initiative, RSGI
Deposited on 2007-04-30, released 2008-05-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-09, with a file datestamp of 2020-09-04.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transcription intermediary factor 1-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: TRIM24, RNF82, TIF1, TIF1A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2yyna_
  • Chain 'B':
    Compound: Transcription intermediary factor 1-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: TRIM24, RNF82, TIF1, TIF1A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2yynb_
  • Chain 'C':
    Compound: Transcription intermediary factor 1-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: TRIM24, RNF82, TIF1, TIF1A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2yync_
  • Chain 'D':
    Compound: Transcription intermediary factor 1-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: TRIM24, RNF82, TIF1, TIF1A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2yynd_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2yynA (A:)
    gssgssgkkkteglvkltpidkrkcerlllflychemslafqdpvpltvpdyykiiknpm
    dlstikkrlqedysmyskpedfvadfrlifqncaefnepdsevanagiklenyfeellkn
    lypekrfpksgpssg
    

    Sequence, based on observed residues (ATOM records): (download)
    >2yynA (A:)
    kltpidkrkcerlllflychemslafqdpvpltvpdyykiiknpmdlstikkrlqedysm
    yskpedfvadfrlifqncaefnepdsevanagiklenyfeellknlypekrfp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2yynB (B:)
    gssgssgkkkteglvkltpidkrkcerlllflychemslafqdpvpltvpdyykiiknpm
    dlstikkrlqedysmyskpedfvadfrlifqncaefnepdsevanagiklenyfeellkn
    lypekrfpksgpssg
    

    Sequence, based on observed residues (ATOM records): (download)
    >2yynB (B:)
    kltpidkrkcerlllflychemslafqdpvpltvpdyykiiknpmdlstikkrlqedysm
    yskpedfvadfrlifqncaefnepdsevanagiklenyfeellknlypekrfpk
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2yynC (C:)
    gssgssgkkkteglvkltpidkrkcerlllflychemslafqdpvpltvpdyykiiknpm
    dlstikkrlqedysmyskpedfvadfrlifqncaefnepdsevanagiklenyfeellkn
    lypekrfpksgpssg
    

    Sequence, based on observed residues (ATOM records): (download)
    >2yynC (C:)
    kltpidkrkcerlllflychemslafqdpvpltvpdyykiiknpmdlstikkrlqedysm
    yskpedfvadfrlifqncaefnepdsevanagiklenyfeellknlypekrfp
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >2yynD (D:)
    gssgssgkkkteglvkltpidkrkcerlllflychemslafqdpvpltvpdyykiiknpm
    dlstikkrlqedysmyskpedfvadfrlifqncaefnepdsevanagiklenyfeellkn
    lypekrfpksgpssg
    

    Sequence, based on observed residues (ATOM records): (download)
    >2yynD (D:)
    kltpidkrkcerlllflychemslafqdpvpltvpdyykiiknpmdlstikkrlqedysm
    yskpedfvadfrlifqncaefnepdsevanagiklenyfeellknlypekrfp