PDB entry 2ypp

View 2ypp on RCSB PDB site
Description: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase in complex with 3 tyrosine molecules
Class: transferase
Keywords: shikimate pathway, transferase, aromatic amino acid biosynthesis, allostery
Deposited on 2012-10-31, released 2013-01-09
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-05-08, with a file datestamp of 2013-05-03.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.14046
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phospho-2-dehydro-3-deoxyheptonate aldolase arog
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2yppa_
  • Chain 'B':
    Compound: phospho-2-dehydro-3-deoxyheptonate aldolase arog
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2yppb_
  • Heterogens: TYR, MN, SO4, GOL, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2yppA (A:)
mnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtv
pseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmp
vvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasaam
nlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnlqt
aeiyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqvia
npvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghq
viwqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvtec
lggaqdisetdlagryetacdprlntqqslelaflvaemlrd

    Sequence, based on observed residues (ATOM records): (download) 
    >2yppA (A:)
mnwtvdipidpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtvps
eivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmpvv
kvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasaamnl
vraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnlqtae
iyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqvianp
vgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghqvi
wqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvteclg
gaqdisetdlagryetacdprlntqqslelaflvaemlrd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2yppB (B:)
mnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtv
pseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmp
vvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasaam
nlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnlqt
aeiyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqvia
npvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghq
viwqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvtec
lggaqdisetdlagryetacdprlntqqslelaflvaemlrd

    Sequence, based on observed residues (ATOM records): (download) 
    >2yppB (B:)
mnwtvdipipslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtvpse
ivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmpvvk
variagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasaamnlv
raltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnlqtaei
yashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqvianpv
gvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghqviw
qcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvteclgg
aqdisetdlagryetacdprlntqqslelaflvaemlrd