PDB entry 2yph

View 2yph on RCSB PDB site
Description: Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H230S, crystallized with 2',3-(RP)- cyclic-AMPS
Class: hydrolase
Keywords: hydrolase, myelin, nervous system
Deposited on 2012-10-30, released 2013-07-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-15, with a file datestamp of 2019-05-10.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2', 3'-cyclic-nucleotide 3'-phosphodiesterase
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16330 (Start-220)
      • engineered mutation (72)
    Domains in SCOPe 2.08: d2ypha_
  • Heterogens: ACT, CL, QQY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2yphA (A:)
gglekdflplyfgwfltkkssetlrkagqvfleelgnhkafkkelrhfisgdepkeklel
vsyfgkrppgvlscttkfcdygkaagaeeyaqqevvkrsygkafklsisalfvtpktaga
qvvltdqelqlwpsdldkpsaseglppgsrahvtlgcaadvqpvqtgldlldilqqvkgg
sqgeavgelprgklyslgkgrwmlsltkkmevkaiftgyyg

    Sequence, based on observed residues (ATOM records): (download) 
    >2yphA (A:)
dflplyfgwfltkkssetlrkagqvfleelgnhkafkkelrhfisgeklelvsyfgkrpp
gvlscttkfcdygkaagaeeyaqqevvkrsygkafklsisalfvtpktagaqvvltdqel
qlwpsdldkpsaseglppgsrahvtlgcaadvqpvqtgldlldilqqvkggsqgeavgel
prgklyslgkgrwmlsltkkmevkaiftgyyg