PDB entry 2ype

View 2ype on RCSB PDB site
Description: Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H309S, crystallized with 2',3'- cyclic AMP
Class: hydrolase
Keywords: hydrolase, myelin, nervous system
Deposited on 2012-10-30, released 2013-07-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-17, with a file datestamp of 2019-07-12.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2', 3'-cyclic-nucleotide 3'-phosphodiesterase
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16330 (Start-220)
      • engineered mutation (151)
    Domains in SCOPe 2.08: d2ypea_
  • Heterogens: ACY, CL, ACK, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ypeA (A:)
gglekdflplyfgwfltkkssetlrkagqvfleelgnhkafkkelrhfisgdepkeklel
vsyfgkrppgvlhcttkfcdygkaagaeeyaqqevvkrsygkafklsisalfvtpktaga
qvvltdqelqlwpsdldkpsaseglppgsrasvtlgcaadvqpvqtgldlldilqqvkgg
sqgeavgelprgklyslgkgrwmlsltkkmevkaiftgyyg

    Sequence, based on observed residues (ATOM records): (download) 
    >2ypeA (A:)
kdflplyfgwfltkkssetlrkagqvfleelgnhkafkkelrhfisgdepkeklelvsyf
gkrppgvlhcttkfcdygkaagaeeyaqqevvkrsygkafklsisalfvtpktagaqvvl
tdqelqlwpsdldkpsaseglppgsrasvtlgcaadvqpvqtgldlldilqqvkqgeavg
elprgklyslgkgrwmlsltkkmevkaiftgyyg