PDB entry 2yog

View 2yog on RCSB PDB site
Description: Plasmodium falciparum thymidylate kinase in complex with a (thio)urea- alpha-deoxythymidine inhibitor
Class: transferase
Keywords: transferase, malaria, inhibitor
Deposited on 2012-10-24, released 2013-07-24
The last revision prior to the SCOPe 2.03 freeze date was dated 2013-07-24, with a file datestamp of 2013-07-19.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.1848
AEROSPACI score: 0.64 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thymidylate kinase
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2yoga_
  • Chain 'B':
    Compound: thymidylate kinase
    Species: PLASMODIUM FALCIPARUM [TaxId:36329]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2yogb_
  • Heterogens: 74X, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2yogA (A:)
mtddkkkgkfivfegldrsgkstqskllveylknnnvevkhlyfpnretgigqiiskylk
mensmsnetihllfsanrwehmneikslllkgiwvvcdryaysgvayssgalnlnktwcm
npdqglikpdvvfylnvppnyaqnrsdygeeiyekvetqkkiyetykhfahedywinida
trkiedihndivkevtkikvepeefnflws

    Sequence, based on observed residues (ATOM records): (download) 
    >2yogA (A:)
dkkkgkfivfegldrsgkstqskllveylknnnvevkhlyfpnretgigqiiskylkmen
smsnetihllfsanrwehmneikslllkgiwvvcdryaysgvayssgalnlnktwcmnpd
qglikpdvvfylnvppnyiyekvetqkkiyetykhfahedywinidatrkiedihndivk
evtkikvepeefnflws

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2yogB (B:)
mtddkkkgkfivfegldrsgkstqskllveylknnnvevkhlyfpnretgigqiiskylk
mensmsnetihllfsanrwehmneikslllkgiwvvcdryaysgvayssgalnlnktwcm
npdqglikpdvvfylnvppnyaqnrsdygeeiyekvetqkkiyetykhfahedywinida
trkiedihndivkevtkikvepeefnflws

    Sequence, based on observed residues (ATOM records): (download) 
    >2yogB (B:)
ddkkkgkfivfegldkstqskllveylknnnvevkhlyfpnretgigqiiskylkmensm
snetihllfsanrwehmneikslllkgiwvvcdryaysgvayssgalnlnktwcmnpdqg
likpdvvfylnvppnyaiyekvetqkkiyetykhfahedywinidatrkiedihndivke
vtkikvepeefnflws