PDB entry 2yn8

View 2yn8 on RCSB PDB site
Description: ephB4 kinase domain inhibitor complex
Class: transferase
Keywords: transferase, unphosphorylated
Deposited on 2012-10-13, released 2013-10-23
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-10-23, with a file datestamp of 2013-10-18.
Experiment type: XRAY
Resolution: 2.11 Å
R-factor: 0.1972
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ephrin type-B receptor 4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54760
      • engineered mutation (208)
      • engineered mutation (275)
    Domains in SCOPe 2.05: d2yn8a_
  • Chain 'B':
    Compound: Ephrin type-B receptor 4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54760
      • engineered mutation (208)
      • engineered mutation (275)
    Domains in SCOPe 2.05: d2yn8b_
  • Heterogens: STU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2yn8A (A:)
gssdpneavrefakeidvsyvkieevigagefgevcrgrlkapgkkescvaiktlkggyt
erqrreflseasimgqfehpniirlegvvtnsmpvmiltefmengaldsflrlndgqftv
iqlvgmlrgiasgmrylaemsyvhrdlaarnilvnsnlvckvsdfglsrfleenssdpte
tsslggkipirwtapeaiafrkftsasdvwsygivmwevmsfgerpywdmsnqdvinaie
qdyrlppppdcptslhqlmldcwqkdrnarprfpqivsaldkmirnpaslkivareng

    Sequence, based on observed residues (ATOM records): (download) 
    >2yn8A (A:)
keidvsyvkieevigagefgevcrgrlkescvaiktlkggyterqrreflseasimgqfe
hpniirlegvvtnsmpvmiltefmengaldsflrlndgqftviqlvgmlrgiasgmryla
emsyvhrdlaarnilvnsnlvckvsdfpirwtapeaiafrkftsasdvwsygivmwevms
fgerpywdmsnqdvinaieqdyrlppppdcptslhqlmldcwqkdrnarprfpqivsald
kmirnpaslkiva

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2yn8B (B:)
gssdpneavrefakeidvsyvkieevigagefgevcrgrlkapgkkescvaiktlkggyt
erqrreflseasimgqfehpniirlegvvtnsmpvmiltefmengaldsflrlndgqftv
iqlvgmlrgiasgmrylaemsyvhrdlaarnilvnsnlvckvsdfglsrfleenssdpte
tsslggkipirwtapeaiafrkftsasdvwsygivmwevmsfgerpywdmsnqdvinaie
qdyrlppppdcptslhqlmldcwqkdrnarprfpqivsaldkmirnpaslkivareng

    Sequence, based on observed residues (ATOM records): (download) 
    >2yn8B (B:)
fakeidvsyvkieevigagefgevcrgrlkapgkkescvaiktlkggyterqrreflsea
simgqfehpniirlegvvtnsmpvmiltefmengaldsflrlndgqftviqlvgmlrgia
sgmrylaemsyvhrdlaarnilvnsnlvckvsdfpirwtapeaiafrkftsasdvwsygi
vmwevmsfgerpywdmsnqdvinaieqdyrlppppdcptslhqlmldcwqkdrnarprfp
qivsaldkmirnpaslkiva