PDB entry 2ymd

View 2ymd on RCSB PDB site
Description: Crystal structure of a mutant binding protein (5HTBP-AChBP) in complex with serotonin (5-hydroxytryptamine)
Class: receptor
Keywords: receptor, pentameric ligand-gated ion channel
Deposited on 2012-10-09, released 2012-12-12
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-01-30, with a file datestamp of 2013-01-25.
Experiment type: XRAY
Resolution: 1.96 Å
R-factor: 0.1595
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-211)
      • conflict (40)
      • engineered mutation (52)
      • conflict (91)
      • conflict (135)
      • conflict (139-140)
    Domains in SCOPe 2.06: d2ymda_
  • Chain 'B':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-End)
      • conflict (40)
      • engineered mutation (52)
      • conflict (91)
      • conflict (135)
      • conflict (139-140)
    Domains in SCOPe 2.06: d2ymdb_
  • Chain 'C':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-211)
      • conflict (40)
      • engineered mutation (52)
      • conflict (91)
      • conflict (135)
      • conflict (139-140)
    Domains in SCOPe 2.06: d2ymdc_
  • Chain 'D':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-211)
      • conflict (40)
      • engineered mutation (52)
      • conflict (91)
      • conflict (135)
      • conflict (139-140)
    Domains in SCOPe 2.06: d2ymdd_
  • Chain 'E':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-211)
      • conflict (40)
      • engineered mutation (52)
      • conflict (91)
      • conflict (135)
      • conflict (139-140)
    Domains in SCOPe 2.06: d2ymde_
  • Chain 'F':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-211)
      • conflict (40)
      • engineered mutation (52)
      • conflict (91)
      • conflict (135)
      • conflict (139-140)
    Domains in SCOPe 2.06: d2ymdf_
  • Chain 'G':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-211)
      • conflict (40)
      • engineered mutation (52)
      • conflict (91)
      • conflict (135)
      • conflict (139-140)
    Domains in SCOPe 2.06: d2ymdg_
  • Chain 'H':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-End)
      • conflict (40)
      • engineered mutation (52)
      • conflict (91)
      • conflict (135)
      • conflict (139-140)
    Domains in SCOPe 2.06: d2ymdh_
  • Chain 'I':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-211)
      • conflict (40)
      • engineered mutation (52)
      • conflict (91)
      • conflict (135)
      • conflict (139-140)
    Domains in SCOPe 2.06: d2ymdi_
  • Chain 'J':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8 (0-211)
      • conflict (40)
      • engineered mutation (52)
      • conflict (91)
      • conflict (135)
      • conflict (139-140)
    Domains in SCOPe 2.06: d2ymdj_
  • Heterogens: SRO, GOL, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ymdA (A:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyweqqrwkl
nslmwdpneygnitdfrtsaadiwtpditayestrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcaltfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngff

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ymdB (B:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyweqqrwkl
nslmwdpneygnitdfrtsaadiwtpditayestrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcaltfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngff

    Sequence, based on observed residues (ATOM records): (download) 
    >2ymdB (B:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyweqqrwkl
nslmwdpneygnitdfrtsaadiwtpditayestrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcaltfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragng

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ymdC (C:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyweqqrwkl
nslmwdpneygnitdfrtsaadiwtpditayestrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcaltfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngff

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ymdD (D:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyweqqrwkl
nslmwdpneygnitdfrtsaadiwtpditayestrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcaltfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngff

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ymdE (E:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyweqqrwkl
nslmwdpneygnitdfrtsaadiwtpditayestrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcaltfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngff

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ymdF (F:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyweqqrwkl
nslmwdpneygnitdfrtsaadiwtpditayestrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcaltfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngff

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ymdG (G:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyweqqrwkl
nslmwdpneygnitdfrtsaadiwtpditayestrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcaltfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngff

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2ymdH (H:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyweqqrwkl
nslmwdpneygnitdfrtsaadiwtpditayestrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcaltfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngff

    Sequence, based on observed residues (ATOM records): (download) 
    >2ymdH (H:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyweqqrwkl
nslmwdpneygnitdfrtsaadiwtpditayestrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcaltfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ymdI (I:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyweqqrwkl
nslmwdpneygnitdfrtsaadiwtpditayestrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcaltfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngff

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ymdJ (J:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyweqqrwkl
nslmwdpneygnitdfrtsaadiwtpditayestrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcaltfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrerragngff