PDB entry 2ym4

View 2ym4 on RCSB PDB site
Description: Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors
Class: transferase
Keywords: transferase, DNA repair, serine/threonine kinase
Deposited on 2011-06-06, released 2012-01-11
The last revision prior to the SCOPe 2.05 freeze date was dated 2012-01-11, with a file datestamp of 2012-01-06.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.2064
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase Chk1
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2ym4a_
  • Heterogens: 4YM, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2ym4A (A:)
    mavpfvedwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicink
    mlnhenvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvy
    lhgigithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellk
    rrefhaepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsapla
    llhkilvenpsaritipdikkdrwynkplkkgakrprvtsggvsespsg
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ym4A (A:)
    pfvedwdlvqtlgegaygevqlavnrvteeavavkivnikkeicinkmlnhenvvkfygh
    qylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigithrdikpenllld
    erdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefhaepvdvwscgivlt
    amlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkilvenpsaritipdi
    kkdrwynkplk