PDB entry 2yla

View 2yla on RCSB PDB site
Description: inhibition of the pneumococcal virulence factor strh and molecular insights into n-glycan recognition and hydrolysis
Deposited on 2011-06-01, released 2011-09-07
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: beta-n-acetylhexosaminidase
    Species: STREPTOCOCCUS PNEUMONIAE [TaxId:170187]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49610 (4-End)
      • expression tag (0-3)
      • engineered mutation (182)
  • Chain 'B':
    Compound: beta-n-acetylhexosaminidase
    Species: STREPTOCOCCUS PNEUMONIAE [TaxId:170187]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49610 (4-End)
      • expression tag (0-3)
      • engineered mutation (182)
  • Chain 'C':
    Compound: beta-n-acetylhexosaminidase
    Species: STREPTOCOCCUS PNEUMONIAE [TaxId:170187]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49610 (4-End)
      • expression tag (2-3)
      • engineered mutation (182)
  • Chain 'D':
    Compound: beta-n-acetylhexosaminidase
    Species: STREPTOCOCCUS PNEUMONIAE [TaxId:170187]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49610 (4-End)
      • expression tag (2-3)
      • engineered mutation (182)
  • Heterogens: EDO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2ylaA (A:)
gshmeklaknkvisidagrkyftlnqlkrivdkaselgysdvhlllgndglrfllddmti
tangktyasddvkkaiiegtkayyddpngtaltqaevtelieyakskdiglipainspgh
mdamlvameklgiknpqahfdkvskttmdlkneeamnfvkaligkymdffagktkifnfg
tdqyandatsaqgwyylkwyqlygkfaeyantlaamakerglqpmafndgfyyedkddvq
fdkdvlisywskgwwgynlaspqylaskgykflntngdwyyilgqkpedgggflkkaien
tgktpfnqlastkypevdlptvgsmlsiwadrpsaeykeeeifelmtafadhnkdyfran
ynalreelakiptnlegyskeslealdaaktalnynlnrnkqaeldtlvanlkaalqglk
pavthsgsldenevaanvetrp

    Sequence, based on observed residues (ATOM records):
    >2ylaA (A:)
gshmeklaknkvisidagrkyftlnqlkrivdkaselgysdvhlllgndglrfllddmti
tangktyasddvkkaiiegtkayyddpngtaltqaevtelieyakskdiglipainspgh
mdamlvameklgiknpqahfdkvskttmdlkneeamnfvkaligkymdffagktkifnfg
tdqyandatsaqgwyylkwyqlygkfaeyantlaamakerglqpmafndgfyyedkddvq
fdkdvlisywskgwwgynlaspqylaskgykflntngdwyyilgqkpedgggflkkaien
tgktpfnqlastkypevdlptvgsmlsiwadrpsaeykeeeifelmtafadhnkdyfran
ynalreelakiptnlskeslealdaaktalnynlnrnkqaeldtlvanlkaalqgl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2ylaB (B:)
gshmeklaknkvisidagrkyftlnqlkrivdkaselgysdvhlllgndglrfllddmti
tangktyasddvkkaiiegtkayyddpngtaltqaevtelieyakskdiglipainspgh
mdamlvameklgiknpqahfdkvskttmdlkneeamnfvkaligkymdffagktkifnfg
tdqyandatsaqgwyylkwyqlygkfaeyantlaamakerglqpmafndgfyyedkddvq
fdkdvlisywskgwwgynlaspqylaskgykflntngdwyyilgqkpedgggflkkaien
tgktpfnqlastkypevdlptvgsmlsiwadrpsaeykeeeifelmtafadhnkdyfran
ynalreelakiptnlegyskeslealdaaktalnynlnrnkqaeldtlvanlkaalqglk
pavthsgsldenevaanvetrp

    Sequence, based on observed residues (ATOM records):
    >2ylaB (B:)
gshmeklaknkvisidagrkyftlnqlkrivdkaselgysdvhlllgndglrfllddmti
tangktyasddvkkaiiegtkayyddpngtaltqaevtelieyakskdiglipainspgh
mdamlvameklgiknpqahfdkvskttmdlkneeamnfvkaligkymdffagktkifnfg
tdqyandatsaqgwyylkwyqlygkfaeyantlaamakerglqpmafndgfyyedkddvq
fdkdvlisywskgwwgynlaspqylaskgykflntngdwyyilgqkpedgggflkkaien
tgktpfnqlastkypevdlptvgsmlsiwadrpsaeykeeeifelmtafadhnkdyfran
ynalreelakiptnlegyskeslealdaaktalnynlnrnkqaeldtlvanlkaalq

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2ylaC (C:)
gshmeklaknkvisidagrkyftlnqlkrivdkaselgysdvhlllgndglrfllddmti
tangktyasddvkkaiiegtkayyddpngtaltqaevtelieyakskdiglipainspgh
mdamlvameklgiknpqahfdkvskttmdlkneeamnfvkaligkymdffagktkifnfg
tdqyandatsaqgwyylkwyqlygkfaeyantlaamakerglqpmafndgfyyedkddvq
fdkdvlisywskgwwgynlaspqylaskgykflntngdwyyilgqkpedgggflkkaien
tgktpfnqlastkypevdlptvgsmlsiwadrpsaeykeeeifelmtafadhnkdyfran
ynalreelakiptnlegyskeslealdaaktalnynlnrnkqaeldtlvanlkaalqglk
pavthsgsldenevaanvetrp

    Sequence, based on observed residues (ATOM records):
    >2ylaC (C:)
hmeklaknkvisidagrkyftlnqlkrivdkaselgysdvhlllgndglrfllddmtita
ngktyasddvkkaiiegtkayyddpngtaltqaevtelieyakskdiglipainspghmd
amlvameklgiknpqahfdkvskttmdlkneeamnfvkaligkymdffagktkifnfgtd
qyandatsaqgwyylkwyqlygkfaeyantlaamakerglqpmafndgfyyedkddvqfd
kdvlisywskgwwgynlaspqylaskgykflntngdwyyilgqkpedgggflkkaientg
ktpfnqlastkypevdlptvgsmlsiwadrpsaeykeeeifelmtafadhnkdyfranyn
alreelakiskeslealdaaktalnynlnrnkqaeldtlvanlkaalq

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2ylaD (D:)
gshmeklaknkvisidagrkyftlnqlkrivdkaselgysdvhlllgndglrfllddmti
tangktyasddvkkaiiegtkayyddpngtaltqaevtelieyakskdiglipainspgh
mdamlvameklgiknpqahfdkvskttmdlkneeamnfvkaligkymdffagktkifnfg
tdqyandatsaqgwyylkwyqlygkfaeyantlaamakerglqpmafndgfyyedkddvq
fdkdvlisywskgwwgynlaspqylaskgykflntngdwyyilgqkpedgggflkkaien
tgktpfnqlastkypevdlptvgsmlsiwadrpsaeykeeeifelmtafadhnkdyfran
ynalreelakiptnlegyskeslealdaaktalnynlnrnkqaeldtlvanlkaalqglk
pavthsgsldenevaanvetrp

    Sequence, based on observed residues (ATOM records):
    >2ylaD (D:)
hmeklaknkvisidagrkyftlnqlkrivdkaselgysdvhlllgndglrfllddmtita
ngktyasddvkkaiiegtkayyddpngtaltqaevtelieyakskdiglipainspghmd
amlvameklgiknpqahfdkvskttmdlkneeamnfvkaligkymdffagktkifnfgtd
qyandatsaqgwyylkwyqlygkfaeyantlaamakerglqpmafndgfyyedkddvqfd
kdvlisywskgwwgynlaspqylaskgykflntngdwyyilgqkpedgggflkkaientg
ktpfnqlastkypevdlptvgsmlsiwadrpsaeykeeeifelmtafadhnkdyfranyn
alreelakiskeslealdaaktalnynlnrnkqaeldtlvanlkaalq