PDB entry 2yl9

View 2yl9 on RCSB PDB site
Description: inhibition of the pneumococcal virulence factor strh and molecular insights into n-glycan recognition and hydrolysis
Deposited on 2011-06-01, released 2011-09-21
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: beta-n-acetylhexosaminidase
    Species: STREPTOCOCCUS PNEUMONIAE [TaxId:170187]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49610 (21-End)
      • expression tag (17-20)
      • engineered mutation (199)
  • Chain 'B':
    Compound: beta-n-acetylhexosaminidase
    Species: STREPTOCOCCUS PNEUMONIAE [TaxId:170187]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49610 (21-End)
      • expression tag (18-20)
      • engineered mutation (199)
  • Chain 'C':
    Compound: beta-n-acetylhexosaminidase
    Species: STREPTOCOCCUS PNEUMONIAE [TaxId:170187]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49610 (21-End)
      • expression tag (17-20)
      • engineered mutation (199)
  • Chain 'D':
    Compound: beta-n-acetylhexosaminidase
    Species: STREPTOCOCCUS PNEUMONIAE [TaxId:170187]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49610 (21-End)
      • expression tag (17-20)
      • engineered mutation (199)
  • Heterogens: EDO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2yl9A (A:)
mgsshhhhhhssglvprgshmeklaknkvisidagrkyftlnqlkrivdkaselgysdvh
lllgndglrfllddmtitangktyasddvkkaiiegtkayyddpngtaltqaevteliey
akskdiglipainspghmdamlvameklgiknpqahfdkvskttmdlkneeamnfvkali
gkymdffagktkifnfgtdqyandatsaqgwyylkwyqlygkfaeyantlaamakerglq
pmafndgfyyedkddvqfdkdvlisywskgwwgynlaspqylaskgykflntngdwyyil
gqkpedgggflkkaientgktpfnqlastkypevdlptvgsmlsiwadrpsaeykeeeif
elmtafadhnkdyfranynalreelakiptnlegyskeslealdaaktalnynlnrnkqa
eldtlvanlkaalqglkpavthsgsldenevaanvet

    Sequence, based on observed residues (ATOM records):
    >2yl9A (A:)
gshmeklaknkvisidagrkyftlnqlkrivdkaselgysdvhlllgndglrfllddmti
tangktyasddvkkaiiegtkayyddpngtaltqaevtelieyakskdiglipainspgh
mdamlvameklgiknpqahfdkvskttmdlkneeamnfvkaligkymdffagktkifnfg
tdqyandatsaqgwyylkwyqlygkfaeyantlaamakerglqpmafndgfyyedkddvq
fdkdvlisywskgwwgynlaspqylaskgykflntngdwyyilgqkpedgggflkkaien
tgktpfnqlastkypevdlptvgsmlsiwadrpsaeykeeeifelmtafadhnkdyfran
ynalreelakipskeslealdaaktalnynlnrnkqaeldtlvanlkaalq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2yl9B (B:)
mgsshhhhhhssglvprgshmeklaknkvisidagrkyftlnqlkrivdkaselgysdvh
lllgndglrfllddmtitangktyasddvkkaiiegtkayyddpngtaltqaevteliey
akskdiglipainspghmdamlvameklgiknpqahfdkvskttmdlkneeamnfvkali
gkymdffagktkifnfgtdqyandatsaqgwyylkwyqlygkfaeyantlaamakerglq
pmafndgfyyedkddvqfdkdvlisywskgwwgynlaspqylaskgykflntngdwyyil
gqkpedgggflkkaientgktpfnqlastkypevdlptvgsmlsiwadrpsaeykeeeif
elmtafadhnkdyfranynalreelakiptnlegyskeslealdaaktalnynlnrnkqa
eldtlvanlkaalqglkpavthsgsldenevaanvet

    Sequence, based on observed residues (ATOM records):
    >2yl9B (B:)
shmeklaknkvisidagrkyftlnqlkrivdkaselgysdvhlllgndglrfllddmtit
angktyasddvkkaiiegtkayyddpngtaltqaevtelieyakskdiglipainspghm
damlvameklgiknpqahfdkvskttmdlkneeamnfvkaligkymdffagktkifnfgt
dqyandatsaqgwyylkwyqlygkfaeyantlaamakerglqpmafndgfyyedkddvqf
dkdvlisywskgwwgynlaspqylaskgykflntngdwyyilgqkpedgggflkkaient
gktpfnqlastkypevdlptvgsmlsiwadrpsaeykeeeifelmtafadhnkdyfrany
nalreelakiskeslealdaaktalnynlnrnkqaeldtlvanlkaalq

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2yl9C (C:)
mgsshhhhhhssglvprgshmeklaknkvisidagrkyftlnqlkrivdkaselgysdvh
lllgndglrfllddmtitangktyasddvkkaiiegtkayyddpngtaltqaevteliey
akskdiglipainspghmdamlvameklgiknpqahfdkvskttmdlkneeamnfvkali
gkymdffagktkifnfgtdqyandatsaqgwyylkwyqlygkfaeyantlaamakerglq
pmafndgfyyedkddvqfdkdvlisywskgwwgynlaspqylaskgykflntngdwyyil
gqkpedgggflkkaientgktpfnqlastkypevdlptvgsmlsiwadrpsaeykeeeif
elmtafadhnkdyfranynalreelakiptnlegyskeslealdaaktalnynlnrnkqa
eldtlvanlkaalqglkpavthsgsldenevaanvet

    Sequence, based on observed residues (ATOM records):
    >2yl9C (C:)
gshmeklaknkvisidagrkyftlnqlkrivdkaselgysdvhlllgndglrfllddmti
tangktyasddvkkaiiegtkayyddpngtaltqaevtelieyakskdiglipainspgh
mdamlvameklgiknpqahfdkvskttmdlkneeamnfvkaligkymdffagktkifnfg
tdqyandatsaqgwyylkwyqlygkfaeyantlaamakerglqpmafndgfyyedkddvq
fdkdvlisywskgwwgynlaspqylaskgykflntngdwyyilgqkpedgggflkkaien
tgktpfnqlastkypevdlptvgsmlsiwadrpsaeykeeeifelmtafadhnkdyfran
ynalreelakiskeslealdaaktalnynlnrnkqaeldtlvanlkaalq

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2yl9D (D:)
mgsshhhhhhssglvprgshmeklaknkvisidagrkyftlnqlkrivdkaselgysdvh
lllgndglrfllddmtitangktyasddvkkaiiegtkayyddpngtaltqaevteliey
akskdiglipainspghmdamlvameklgiknpqahfdkvskttmdlkneeamnfvkali
gkymdffagktkifnfgtdqyandatsaqgwyylkwyqlygkfaeyantlaamakerglq
pmafndgfyyedkddvqfdkdvlisywskgwwgynlaspqylaskgykflntngdwyyil
gqkpedgggflkkaientgktpfnqlastkypevdlptvgsmlsiwadrpsaeykeeeif
elmtafadhnkdyfranynalreelakiptnlegyskeslealdaaktalnynlnrnkqa
eldtlvanlkaalqglkpavthsgsldenevaanvet

    Sequence, based on observed residues (ATOM records):
    >2yl9D (D:)
gshmeklaknkvisidagrkyftlnqlkrivdkaselgysdvhlllgndglrfllddmti
tangktyasddvkkaiiegtkayyddpngtaltqaevtelieyakskdiglipainspgh
mdamlvameklgiknpqahfdkvskttmdlkneeamnfvkaligkymdffagktkifnfg
tdqyandatsaqgwyylkwyqlygkfaeyantlaamakerglqpmafndgfyyedkddvq
fdkdvlisywskgwwgynlaspqylaskgykflntngdwyyilgqkpedgggflkkaien
tgktpfnqlastkypevdlptvgsmlsiwadrpsaeykeeeifelmtafadhnkdyfran
ynalreelakipskeslealdaaktalnynlnrnkqaeldtlvanlkaalq