PDB entry 2yks

View 2yks on RCSB PDB site
Description: pentameric ligand gated ion channel elic mutant f246a
Deposited on 2011-05-30, released 2011-07-06
The last revision was dated 2011-11-16, with a file datestamp of 2011-11-11.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: 0.243
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cys-loop ligand-gated ion channel
    Species: Erwinia chrysanthemi [TaxId:556]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0C7B7
      • engineered mutation (245)
      • conflict (287)
  • Chain 'B':
    Compound: cys-loop ligand-gated ion channel
    Species: Erwinia chrysanthemi [TaxId:556]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0C7B7
      • engineered mutation (245)
      • conflict (287)
  • Chain 'C':
    Compound: cys-loop ligand-gated ion channel
    Species: Erwinia chrysanthemi [TaxId:556]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0C7B7
      • engineered mutation (245)
      • conflict (287)
  • Chain 'D':
    Compound: cys-loop ligand-gated ion channel
    Species: Erwinia chrysanthemi [TaxId:556]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0C7B7
      • engineered mutation (245)
      • conflict (287)
  • Chain 'E':
    Compound: cys-loop ligand-gated ion channel
    Species: Erwinia chrysanthemi [TaxId:556]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0C7B7
      • engineered mutation (245)
      • conflict (287)
  • Chain 'F':
    Compound: cys-loop ligand-gated ion channel
    Species: Erwinia chrysanthemi [TaxId:556]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0C7B7
      • engineered mutation (245)
      • conflict (287)
  • Chain 'G':
    Compound: cys-loop ligand-gated ion channel
    Species: Erwinia chrysanthemi [TaxId:556]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0C7B7
      • engineered mutation (245)
      • conflict (287)
  • Chain 'H':
    Compound: cys-loop ligand-gated ion channel
    Species: Erwinia chrysanthemi [TaxId:556]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0C7B7
      • engineered mutation (245)
      • conflict (287)
  • Chain 'I':
    Compound: cys-loop ligand-gated ion channel
    Species: Erwinia chrysanthemi [TaxId:556]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0C7B7
      • engineered mutation (245)
      • conflict (287)
  • Chain 'J':
    Compound: cys-loop ligand-gated ion channel
    Species: Erwinia chrysanthemi [TaxId:556]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0C7B7
      • engineered mutation (245)
      • conflict (287)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2yksA (A:)
apadnaadarpvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliven
tqierwinnglwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfp
fdrqqfvlelepfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssv
qpnqnefsritvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmlt
vvayaaytsnilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcr
lafplgflaigcvlvirgitl

    Sequence, based on observed residues (ATOM records):
    >2yksA (A:)
pvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliventqierwinng
lwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfpfdrqqfvlel
epfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssvqpnqnefsri
tvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmltvvayaaytsn
ilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcrlafplgflai
gcvlvi

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2yksB (B:)
apadnaadarpvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliven
tqierwinnglwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfp
fdrqqfvlelepfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssv
qpnqnefsritvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmlt
vvayaaytsnilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcr
lafplgflaigcvlvirgitl

    Sequence, based on observed residues (ATOM records):
    >2yksB (B:)
pvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliventqierwinng
lwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfpfdrqqfvlel
epfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssvqpnqnefsri
tvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmltvvayaaytsn
ilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcrlafplgflai
gcvlvi

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2yksC (C:)
apadnaadarpvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliven
tqierwinnglwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfp
fdrqqfvlelepfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssv
qpnqnefsritvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmlt
vvayaaytsnilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcr
lafplgflaigcvlvirgitl

    Sequence, based on observed residues (ATOM records):
    >2yksC (C:)
pvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliventqierwinng
lwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfpfdrqqfvlel
epfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssvqpnqnefsri
tvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmltvvayaaytsn
ilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcrlafplgflai
gcvlvi

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2yksD (D:)
apadnaadarpvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliven
tqierwinnglwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfp
fdrqqfvlelepfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssv
qpnqnefsritvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmlt
vvayaaytsnilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcr
lafplgflaigcvlvirgitl

    Sequence, based on observed residues (ATOM records):
    >2yksD (D:)
pvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliventqierwinng
lwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfpfdrqqfvlel
epfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssvqpnqnefsri
tvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmltvvayaaytsn
ilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcrlafplgflai
gcvlvi

  • Chain 'E':
    Sequence, based on SEQRES records:
    >2yksE (E:)
apadnaadarpvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliven
tqierwinnglwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfp
fdrqqfvlelepfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssv
qpnqnefsritvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmlt
vvayaaytsnilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcr
lafplgflaigcvlvirgitl

    Sequence, based on observed residues (ATOM records):
    >2yksE (E:)
pvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliventqierwinng
lwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfpfdrqqfvlel
epfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssvqpnqnefsri
tvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmltvvayaaytsn
ilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcrlafplgflai
gcvlvi

  • Chain 'F':
    Sequence, based on SEQRES records:
    >2yksF (F:)
apadnaadarpvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliven
tqierwinnglwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfp
fdrqqfvlelepfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssv
qpnqnefsritvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmlt
vvayaaytsnilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcr
lafplgflaigcvlvirgitl

    Sequence, based on observed residues (ATOM records):
    >2yksF (F:)
pvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliventqierwinng
lwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfpfdrqqfvlel
epfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssvqpnqnefsri
tvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmltvvayaaytsn
ilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcrlafplgflai
gcvlvi

  • Chain 'G':
    Sequence, based on SEQRES records:
    >2yksG (G:)
apadnaadarpvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliven
tqierwinnglwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfp
fdrqqfvlelepfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssv
qpnqnefsritvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmlt
vvayaaytsnilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcr
lafplgflaigcvlvirgitl

    Sequence, based on observed residues (ATOM records):
    >2yksG (G:)
pvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliventqierwinng
lwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfpfdrqqfvlel
epfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssvqpnqnefsri
tvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmltvvayaaytsn
ilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcrlafplgflai
gcvlvi

  • Chain 'H':
    Sequence, based on SEQRES records:
    >2yksH (H:)
apadnaadarpvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliven
tqierwinnglwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfp
fdrqqfvlelepfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssv
qpnqnefsritvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmlt
vvayaaytsnilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcr
lafplgflaigcvlvirgitl

    Sequence, based on observed residues (ATOM records):
    >2yksH (H:)
pvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliventqierwinng
lwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfpfdrqqfvlel
epfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssvqpnqnefsri
tvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmltvvayaaytsn
ilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcrlafplgflai
gcvlvi

  • Chain 'I':
    Sequence, based on SEQRES records:
    >2yksI (I:)
apadnaadarpvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliven
tqierwinnglwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfp
fdrqqfvlelepfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssv
qpnqnefsritvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmlt
vvayaaytsnilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcr
lafplgflaigcvlvirgitl

    Sequence, based on observed residues (ATOM records):
    >2yksI (I:)
pvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliventqierwinng
lwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfpfdrqqfvlel
epfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssvqpnqnefsri
tvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmltvvayaaytsn
ilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcrlafplgflai
gcvlvi

  • Chain 'J':
    Sequence, based on SEQRES records:
    >2yksJ (J:)
apadnaadarpvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliven
tqierwinnglwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfp
fdrqqfvlelepfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssv
qpnqnefsritvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmlt
vvayaaytsnilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcr
lafplgflaigcvlvirgitl

    Sequence, based on observed residues (ATOM records):
    >2yksJ (J:)
pvdvsvsifinkiygvntleqtykvdgyivaqwtgkprktpgdkpliventqierwinng
lwvpalefinvvgspdtgnkrlmlfpdgrviynarflgsfsndmdfrlfpfdrqqfvlel
epfsynnqqlrfsdiqvytenidneeidewwirkasthisdirydhlssvqpnqnefsri
tvridavrnpsyylwsfilplgliiaaswsvfwlesfserlqtsftlmltvvayaaytsn
ilprlpyttvidqmiiagygsifaailliifahhrqangveddlliqrcrlafplgflai
gcvlvi