PDB entry 2yki

View 2yki on RCSB PDB site
Description: Tricyclic series of Hsp90 inhibitors
Class: chaperone
Keywords: chaperone, inhibition
Deposited on 2011-05-27, released 2011-10-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-06-13, with a file datestamp of 2018-06-08.
Experiment type: XRAY
Resolution: 1.67 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heat shock protein HSP 90-alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07900 (3-208)
      • expression tag (2)
    Domains in SCOPe 2.08: d2ykia1, d2ykia2
  • Heterogens: YKI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ykiA (A:)
ghmetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskldsgk
elhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadismigqf
gvgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedq
teyleerrikeivkkhsqfigypitlfve

    Sequence, based on observed residues (ATOM records): (download) 
    >2ykiA (A:)
metfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskldsgkel
hinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadismigqfgv
gfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedqte
yleerrikeivkkhsqfigypitlfve