PDB entry 2yjx
View 2yjx on RCSB PDB site
Description: tricyclic series of hsp90 inhibitors
Class: chaperone
Keywords: chaperone, hsp90, molecular chaperone, inhibition
Deposited on
2011-05-24, released
2011-10-19
The last revision prior to the SCOPe 2.08 freeze date was dated
2011-11-02, with a file datestamp of
2011-10-28.
Experiment type: XRAY
Resolution: 1.83 Å
R-factor: 0.1761
AEROSPACI score: 0.53
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Heat shock protein HSP 90-alpha
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2yjxa1, d2yjxa2 - Heterogens: YJX, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2yjxA (A:)
ghmetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskldsgk
elhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadismigqf
gvgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedq
teyleerrikeivkkhsqfigypitlfve
Sequence, based on observed residues (ATOM records): (download)
>2yjxA (A:)
metfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskldsgkel
hinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadismigqfgv
gfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedqte
yleerrikeivkkhsqfigypitlfve