PDB entry 2yiy

View 2yiy on RCSB PDB site
Description: crystal structure of compound 8 bound to tak1-tab
Deposited on 2011-05-17, released 2012-05-23
The last revision was dated 2019-03-27, with a file datestamp of 2019-03-22.
Experiment type: XRAY
Resolution: 2.49 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: mitogen-activated protein kinase kinase kinase 7, tgf-beta-activated kinase 1 and map3k7-binding protein 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O43318 (4-276)
      • expression tag (0-3)
    • Uniprot Q15750 (277-End)
  • Heterogens: YIY, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2yiyA (A:)
    slhmidykeieveevvgrgafgvvckakwrakdvaikqieseserkafivelrqlsrvnh
    pnivklygaclnpvclvmeyaeggslynvlhgaeplpyytaahamswclqcsqgvaylhs
    mqpkalihrdlkppnlllvaggtvlkicdfgtacdiqthmtnnkgsaawmapevfegsny
    sekcdvfswgiilwevitrrkpfdeiggpafrimwavhngtrppliknlpkpieslmtrc
    wskdpsqrpsmeeivkimthlmryfpgadeplqypcqhslppgedgrvepyvdfaefyrl
    wsvdhge
    

    Sequence, based on observed residues (ATOM records):
    >2yiyA (A:)
    slhmidykeieveevvgrgafgvvckakwrakdvaikqieseserkafivelrqlsrvnh
    pnivklygaclnpvclvmeyaeggslynvlhgaeplpyytaahamswclqcsqgvaylhs
    mqpkalihrdlkppnlllvaggtvlkicdfggsaawmapevfegsnysekcdvfswgiil
    wevitrrkpfdeiggpafrimwavhngtrppliknlpkpieslmtrcwskdpsqrpsmee
    ivkimthlmryfpgadeplqypcqhslppgedgrvepyvdfaefyrlwsvdhg