PDB entry 2yii

View 2yii on RCSB PDB site
Description: Manipulating the regioselectivity of phenylalanine aminomutase: new insights into the reaction mechanism of MIO-dependent enzymes from structure-guided directed evolution
Class: lyase
Keywords: lyase
Deposited on 2011-05-13, released 2011-11-09
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-01-30, with a file datestamp of 2013-01-25.
Experiment type: XRAY
Resolution: 2.18 Å
R-factor: 0.18053
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phenylalanine ammonia-lyase
    Species: TAXUS WALLICHIANA VAR. CHINENSIS [TaxId:29808]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q68G84
      • chromophore (194)
    • Uniprot Q68G84
      • chromophore (194)
    Domains in SCOPe 2.05: d2yiia_
  • Chain 'B':
    Compound: phenylalanine ammonia-lyase
    Species: TAXUS WALLICHIANA VAR. CHINENSIS [TaxId:29808]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q68G84
      • chromophore (194)
    • Uniprot Q68G84
      • chromophore (194)
    Domains in SCOPe 2.05: d2yiib_
  • Chain 'C':
    Compound: phenylalanine ammonia-lyase
    Species: TAXUS WALLICHIANA VAR. CHINENSIS [TaxId:29808]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q68G84
      • chromophore (194)
    • Uniprot Q68G84
      • chromophore (194)
    Domains in SCOPe 2.05: d2yiic_
  • Chain 'D':
    Compound: phenylalanine ammonia-lyase
    Species: TAXUS WALLICHIANA VAR. CHINENSIS [TaxId:29808]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q68G84
      • chromophore (194)
    • Uniprot Q68G84
      • chromophore (194)
    Domains in SCOPe 2.05: d2yiid_
  • Heterogens: BME, FMT, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2yiiA (A:)
mgsshhhhhhssglvprgshmgfavesrshvkdilglinafnevkkitvdgttpitvahv
aalarrhdvkvaleaeqcrarvetcsswvqrkaedgadiygvttgfgacssrrtnrlsel
qeslircllagvftkgcapsvdelpatatrsamllrlnsftygcsgirwevmealeklln
snvspkvplrgsvsasgdliplayiaglligkpsviarigddvevpapealsrvglrpfk
lqakeglalvngtsfatavastvmydanvllllvetlcgmfcevifgreefahplihkvk
phpgqiesaellewllrsspfqelsreyysidklkkpkqdryalrsspqwlaplvqtird
atttvetevnsandnpiidhandralhganfqgsavgfymdyvriavaglgkllfaqfte
lmieyysnglpgnlslgpdlsvdyglkgldiamaaysselqylanpvtthvhsaeqhnqd
inslalisarkteealdilklmiashltamcqavdlrqleealvkvvenvvstladecgl
pndtkarllyvakavpvytylespcdptlplllglkqscfdtilalhkkdgietdtlvdr
laefekrlsdrlenemtavrvlyekkghktadnndalvriqgskflpfyrfvreeldtgv
msarreqtpqedvqkvfdaiadgritvpllhclqgflgqpngcangv

    Sequence, based on observed residues (ATOM records): (download) 
    >2yiiA (A:)
shvkdilglinafnevkkitvdgttpitvahvaalarrhdvkvaleaeqcrarvetcssw
vqrkaedgadiygvttgfgacssrrtnrlselqeslircllagvftkvdelpatatrsam
llrlnsftygcsgirwevmealekllnsnvspkvplrgsvsasgdliplayiaglligkp
sviarigddvevpapealsrvglrpfklqakeglalvngtsfatavastvmydanvllll
vetlcgmfcevifgreefahplihkvkphpgqiesaellewllrsspfqelsreyysidk
lkkpkqdryalrsspqwlaplvqtirdatttvetevnsandnpiidhandralhganfqg
savgfymdyvriavaglgkllfaqftelmieyysnglpgnlslgpdlsvdyglkgldiam
aaysselqylanpvtthvhsaeqhnqdinslalisarkteealdilklmiashltamcqa
vdlrqleealvkvvenvvstladecglpndtkarllyvakavpvytylespcdptlplll
glkqscfdtilalhkdtlvdrlaefekrlsdrlenemtavrvlyekvriqgskflpfyrf
vreeldtgvmsarreqtpqedvqkvfdaiadgritvpllhclqgfl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2yiiB (B:)
mgsshhhhhhssglvprgshmgfavesrshvkdilglinafnevkkitvdgttpitvahv
aalarrhdvkvaleaeqcrarvetcsswvqrkaedgadiygvttgfgacssrrtnrlsel
qeslircllagvftkgcapsvdelpatatrsamllrlnsftygcsgirwevmealeklln
snvspkvplrgsvsasgdliplayiaglligkpsviarigddvevpapealsrvglrpfk
lqakeglalvngtsfatavastvmydanvllllvetlcgmfcevifgreefahplihkvk
phpgqiesaellewllrsspfqelsreyysidklkkpkqdryalrsspqwlaplvqtird
atttvetevnsandnpiidhandralhganfqgsavgfymdyvriavaglgkllfaqfte
lmieyysnglpgnlslgpdlsvdyglkgldiamaaysselqylanpvtthvhsaeqhnqd
inslalisarkteealdilklmiashltamcqavdlrqleealvkvvenvvstladecgl
pndtkarllyvakavpvytylespcdptlplllglkqscfdtilalhkkdgietdtlvdr
laefekrlsdrlenemtavrvlyekkghktadnndalvriqgskflpfyrfvreeldtgv
msarreqtpqedvqkvfdaiadgritvpllhclqgflgqpngcangv

    Sequence, based on observed residues (ATOM records): (download) 
    >2yiiB (B:)
rshvkdilglinafnevkkitvdgttpitvahvaalarrhdvkvaleaeqcrarvetcss
wvqrkaedgadiygvttgfgacssrrtnrlselqeslircllagvftvdelpatatrsam
llrlnsftygcsgirwevmealekllnsnvspkvplrgsvsasgdliplayiaglligkp
sviarigddvevpapealsrvglrpfklqakeglalvngtsfatavastvmydanvllll
vetlcgmfcevifgreefahplihkvkphpgqiesaellewllrsspfqelsreyysidk
lkkpkqdryalrsspqwlaplvqtirdatttvetevnsandnpiidhandralhganfqg
savgfymdyvriavaglgkllfaqftelmieyysnglpgnlslgpdlsvdyglkgldiam
aaysselqylanpvtthvhsaeqhnqdinslalisarkteealdilklmiashltamcqa
vdlrqleealvkvvenvvstladecglpndtkarllyvakavpvytylespcdptlplll
glkqscfdtilalhkdgietdtlvdrlaefekrlsdrlenemtavrvlyekkvriqgskf
lpfyrfvreeldtgvmsarreqtpqedvqkvfdaiadgritvpllhclqgfl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2yiiC (C:)
mgsshhhhhhssglvprgshmgfavesrshvkdilglinafnevkkitvdgttpitvahv
aalarrhdvkvaleaeqcrarvetcsswvqrkaedgadiygvttgfgacssrrtnrlsel
qeslircllagvftkgcapsvdelpatatrsamllrlnsftygcsgirwevmealeklln
snvspkvplrgsvsasgdliplayiaglligkpsviarigddvevpapealsrvglrpfk
lqakeglalvngtsfatavastvmydanvllllvetlcgmfcevifgreefahplihkvk
phpgqiesaellewllrsspfqelsreyysidklkkpkqdryalrsspqwlaplvqtird
atttvetevnsandnpiidhandralhganfqgsavgfymdyvriavaglgkllfaqfte
lmieyysnglpgnlslgpdlsvdyglkgldiamaaysselqylanpvtthvhsaeqhnqd
inslalisarkteealdilklmiashltamcqavdlrqleealvkvvenvvstladecgl
pndtkarllyvakavpvytylespcdptlplllglkqscfdtilalhkkdgietdtlvdr
laefekrlsdrlenemtavrvlyekkghktadnndalvriqgskflpfyrfvreeldtgv
msarreqtpqedvqkvfdaiadgritvpllhclqgflgqpngcangv

    Sequence, based on observed residues (ATOM records): (download) 
    >2yiiC (C:)
shvkdilglinafnevkkitvdgttpitvahvaalarrhdvkvaleacrarvetcsswvq
rkaedgadiygvttgfgacssrrtnrlselqeslircllagvftvdelpatatrsamllr
lnsftygcsgirwevmealekllnsnvspkvplrgsvsasgdliplayiaglligkpsvi
arigddvevpapealsrvglrpfklqakeglalvngtsfatavastvmydanvllllvet
lcgmfcevifgreefahplihkvkphpgqiesaellewllrsspfqelsreyysidklkk
pkqdryalrsspqwlaplvqtirdatttvetevnsandnpiidhandralhganfqgsav
gfymdyvriavaglgkllfaqftelmieyysnglpgnlslgpdlsvdyglkgldiamaay
sselqylanpvtthvhsaeqhnqdinslalisarkteealdilklmiashltamcqavdl
rqleealvkvvenvvstladecglpndtkarllyvakavpvytylespcdptlplllglk
qscfdtilalhkketdtlvdrlaefekrlsdrlenemtavrvlyekkvriqgskflpfyr
fvreeldtgvmsarreqtpqedvqkvfdaiadgritvpllhclqgflg

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2yiiD (D:)
mgsshhhhhhssglvprgshmgfavesrshvkdilglinafnevkkitvdgttpitvahv
aalarrhdvkvaleaeqcrarvetcsswvqrkaedgadiygvttgfgacssrrtnrlsel
qeslircllagvftkgcapsvdelpatatrsamllrlnsftygcsgirwevmealeklln
snvspkvplrgsvsasgdliplayiaglligkpsviarigddvevpapealsrvglrpfk
lqakeglalvngtsfatavastvmydanvllllvetlcgmfcevifgreefahplihkvk
phpgqiesaellewllrsspfqelsreyysidklkkpkqdryalrsspqwlaplvqtird
atttvetevnsandnpiidhandralhganfqgsavgfymdyvriavaglgkllfaqfte
lmieyysnglpgnlslgpdlsvdyglkgldiamaaysselqylanpvtthvhsaeqhnqd
inslalisarkteealdilklmiashltamcqavdlrqleealvkvvenvvstladecgl
pndtkarllyvakavpvytylespcdptlplllglkqscfdtilalhkkdgietdtlvdr
laefekrlsdrlenemtavrvlyekkghktadnndalvriqgskflpfyrfvreeldtgv
msarreqtpqedvqkvfdaiadgritvpllhclqgflgqpngcangv

    Sequence, based on observed residues (ATOM records): (download) 
    >2yiiD (D:)
shvkdilglinafnevkkitvdgttpitvahvaalarrhdvkvaleaeqcrarvetcssw
vqrkaedgadiygvttgfgacssrrtnrlselqeslircllagvftkvdelpatatrsam
llrlnsftygcsgirwevmealekllnsnvspkvplrgsvsasgdliplayiaglligkp
sviarigddvevpapealsrvglrpfklqakeglalvngtsfatavastvmydanvllll
vetlcgmfcevifgreefahplihkvkphpgqiesaellewllrsspfqelsreyysidk
lkkpkqdryalrsspqwlaplvqtirdatttvetevnsandnpiidhandralhganfqg
savgfymdyvriavaglgkllfaqftelmieyysnglpgnlslgpdlsvdyglkgldiam
aaysselqylanpvtthvhsaeqhnqdinslalisarkteealdilklmiashltamcqa
vdlrqleealvkvvenvvstladecglpndtkarllyvakavpvytylespcdptlplll
glkqscfdtilalhetdtlvdrlaefekrlsdrlenemtavrvlyekvriqgskflpfyr
fvreeldtgvmsarreqtpqedvqkvfdaiadgritvpllhclqgfl