PDB entry 2yhw

View 2yhw on RCSB PDB site
Description: high-resolution crystal structures of n-acetylmannosamine kinase: insights about substrate specificity, activity and inhibitor modelling.
Deposited on 2011-05-08, released 2012-02-29
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 1.64 Å
R-factor: N/A
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y223 (28-End)
      • expression tag (27)
  • Heterogens: BM3, ZN, 2PE, EDO, CA, PGE, ACT, CL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2yhwA (A:)
    mgsshhhhhhssglvprgshmenlyfqgtlsalavdlggtnlrvaivsmkgeivkkytqf
    npktyeerinlilqmcveaaaeavklncrilgvgistggrvnpregivlhstkliqewns
    vdlrtplsdtlhlpvwvdndgncaalaerkfgqgkglenfvtlitgtgigggiihqheli
    hgssfcaaelghlvvslxgpdcscgshgcieayasgmalqreakklhdedlllvegmsvp
    kdeavgalhliqaaklgnakaqsilrtagtalglgvvnilhtmnpslvilsgvlashyih
    ivkdvirqqalssvqdvdvvvsdlvdpallgaasmvldyttrr
    

    Sequence, based on observed residues (ATOM records):
    >2yhwA (A:)
    gtlsalavdlggtnlrvaivsmkgeivkkytqfnpktyeerinlilqmcveaaaeavkln
    crilgvgistggrvnpregivlhstkliqewnsvdlrtplsdtlhlpvwvdndgncaala
    erkfgqgkglenfvtlitgtgigggiihqhelihgssfcaaelghlvvslxgpdcscgsh
    gcieayasgmalqreakklhdedlllvegmsvavgalhliqaaklgnakaqsilrtagta
    lglgvvnilhtmnpslvilsgvlashyihivkdvirqqalssvqdvdvvvsdlvdpallg
    aasmvldyt