PDB entry 2yel

View 2yel on RCSB PDB site
Description: crystal structure of the first bromodomain of human brd4 with the inhibitor gw841819x
Class: signaling protein
Keywords: signaling protein, histone, epigenetic reader
Deposited on 2011-03-25, released 2011-06-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-06-15, with a file datestamp of 2011-06-10.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: 0.16757
AEROSPACI score: 0.6 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: human brd4
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot O60885 (2-126)
    • expression tag (0-1)
  Domains in SCOPe 2.08: d2yela1, d2yela2
• Heterogens: EDO, WSH, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2yelA (A:)
  smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
  ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
  nelptee