PDB entry 2ycw

View 2ycw on RCSB PDB site
Description: turkey beta1 adrenergic receptor with stabilising mutations and bound antagonist carazolol
Class: receptor
Keywords: gpcr, receptor, transducer, antagonist bound form, integral membrane protein, g-protein coupled receptor, thermostabilising point mutations, seven-helix receptor, 7tm receptor
Deposited on 2011-03-17, released 2011-06-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-04-03, with a file datestamp of 2019-03-29.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: beta-1 adrenergic receptor
    Species: Meleagris gallopavo [TaxId:9103]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07700 (218-End)
      • engineered mutation (37)
      • engineered mutation (59)
      • engineered mutation (85)
      • engineered mutation (196)
      • engineered mutation (221)
      • engineered mutation (266)
      • engineered mutation (277)
      • engineered mutation (297)
    Domains in SCOPe 2.08: d2ycwa_
  • Chain 'B':
    Compound: beta-1 adrenergic receptor
    Species: Meleagris gallopavo [TaxId:9103]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07700 (218-End)
      • engineered mutation (37)
      • engineered mutation (59)
      • engineered mutation (85)
      • engineered mutation (196)
      • engineered mutation (221)
      • engineered mutation (266)
      • engineered mutation (277)
      • engineered mutation (297)
    Domains in SCOPe 2.08: d2ycwb_
  • Heterogens: CAU, 2CV, NA

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ycwA (A:)
mgaellsqqweagmsllmalvvllivagnvlviaaigstqrlqtltnlfitslacadlvv
gllvvpfgatlvvrgtwlwgsflcelwtsldvlcvtasietlcviaidrylaitspfryq
slmtrarakviictvwaisalvsflpimmhwwrdedpqalkcyqdpgccdfvtnrayaia
ssiisfyipllimifvalrvyreakeqirkidraskrkrvmlmrehkalktlgiimgvft
lcwlpfflvnivnvfnrdlvpdwlfvafnwlgyansamnpiiycrspdfrkafkrllafp
rkadrrlhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2ycwA (A:)
aellsqqweagmsllmalvvllivagnvlviaaigstqrlqtltnlfitslacadlvvgl
lvvpfgatlvvrgtwlwgsflcelwtsldvlcvtasietlcviaidrylaitspfryqsl
mtrarakviictvwaisalvsflpimmhwwrdedpqalkcyqdpgccdfvtnrayaiass
iisfyipllimifvalrvyreakeqirkidraskrkrvmlmrehkalktlgiimgvftlc
wlpfflvnivnvfnrdlvpdwlfvafnwlgyansamnpiiycrspdfrkafkrllaf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ycwB (B:)
mgaellsqqweagmsllmalvvllivagnvlviaaigstqrlqtltnlfitslacadlvv
gllvvpfgatlvvrgtwlwgsflcelwtsldvlcvtasietlcviaidrylaitspfryq
slmtrarakviictvwaisalvsflpimmhwwrdedpqalkcyqdpgccdfvtnrayaia
ssiisfyipllimifvalrvyreakeqirkidraskrkrvmlmrehkalktlgiimgvft
lcwlpfflvnivnvfnrdlvpdwlfvafnwlgyansamnpiiycrspdfrkafkrllafp
rkadrrlhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2ycwB (B:)
aellsqqweagmsllmalvvllivagnvlviaaigstqrlqtltnlfitslacadlvvgl
lvvpfgatlvvrgtwlwgsflcelwtsldvlcvtasietlcviaidrylaitspfryqsl
mtrarakviictvwaisalvsflpimmhwwrdedpqalkcyqdpgccdfvtnrayaiass
iisfyipllimifvalrvyreakeqirkidraskrkrvmlmrehkalktlgiimgvftlc
wlpfflvnivnvfnrdlvpdwlfvafnwlgyansamnpiiycrspdfrkafkrllaf