PDB entry 2ycp

View 2ycp on RCSB PDB site
Description: F448H mutant of tyrosine phenol-lyase from Citrobacter freundii in complex with quinonoid intermediate formed with 3-fluoro-L-tyrosine
Class: lyase
Keywords: lyase, pyridoxal 5'-phosphate dependent enzyme, beta-elimination
Deposited on 2011-03-16, released 2011-09-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tyrosine phenol-lyase
    Species: Citrobacter freundii [TaxId:546]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P31013 (0-455)
      • engineered mutation (447)
    Domains in SCOPe 2.08: d2ycpa_
  • Chain 'B':
    Compound: tyrosine phenol-lyase
    Species: Citrobacter freundii [TaxId:546]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P31013 (0-455)
      • engineered mutation (447)
    Domains in SCOPe 2.08: d2ycpb_
  • Chain 'C':
    Compound: tyrosine phenol-lyase
    Species: Citrobacter freundii [TaxId:546]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P31013 (0-455)
      • engineered mutation (447)
    Domains in SCOPe 2.08: d2ycpc_
  • Chain 'D':
    Compound: tyrosine phenol-lyase
    Species: Citrobacter freundii [TaxId:546]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P31013 (0-455)
      • engineered mutation (447)
    Domains in SCOPe 2.08: d2ycpd_
  • Heterogens: P61, PGE, PG4, K, EDO, 1PE, P33, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ycpA (A:)
mnypaepfriksvetvsmiprderlkkmqeagyntfllnskdiyidlltdsgtnamsdkq
wagmmmgdeayagsenfyhlertvqelfgfkhivpthqgrgaenllsqlaikpgqyvagn
myftttryhqekngavfvdivrdeahdaglniafkgdidlkklqklidekgaeniayicl
avtvnlaggqpvsmanmravrelteahgikvfydatrcvenayfikeqeqgfenksiaei
vhemfsyadgctmsgkkdclvniggflcmnddemfssakelvvvyegmpsygglagrdme
amaiglreamqyeyiehrvkqvrylgdklkaagvpivepvgghavfldarrfcehltqde
fpaqslaasiyvetgvrsmergiisagrnnvtgehhrpkletvrltiprrvytyahmdvv
adgiiklyqhkedirglkfiyepkqlrhftarfdyi

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ycpB (B:)
mnypaepfriksvetvsmiprderlkkmqeagyntfllnskdiyidlltdsgtnamsdkq
wagmmmgdeayagsenfyhlertvqelfgfkhivpthqgrgaenllsqlaikpgqyvagn
myftttryhqekngavfvdivrdeahdaglniafkgdidlkklqklidekgaeniayicl
avtvnlaggqpvsmanmravrelteahgikvfydatrcvenayfikeqeqgfenksiaei
vhemfsyadgctmsgkkdclvniggflcmnddemfssakelvvvyegmpsygglagrdme
amaiglreamqyeyiehrvkqvrylgdklkaagvpivepvgghavfldarrfcehltqde
fpaqslaasiyvetgvrsmergiisagrnnvtgehhrpkletvrltiprrvytyahmdvv
adgiiklyqhkedirglkfiyepkqlrhftarfdyi

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ycpC (C:)
mnypaepfriksvetvsmiprderlkkmqeagyntfllnskdiyidlltdsgtnamsdkq
wagmmmgdeayagsenfyhlertvqelfgfkhivpthqgrgaenllsqlaikpgqyvagn
myftttryhqekngavfvdivrdeahdaglniafkgdidlkklqklidekgaeniayicl
avtvnlaggqpvsmanmravrelteahgikvfydatrcvenayfikeqeqgfenksiaei
vhemfsyadgctmsgkkdclvniggflcmnddemfssakelvvvyegmpsygglagrdme
amaiglreamqyeyiehrvkqvrylgdklkaagvpivepvgghavfldarrfcehltqde
fpaqslaasiyvetgvrsmergiisagrnnvtgehhrpkletvrltiprrvytyahmdvv
adgiiklyqhkedirglkfiyepkqlrhftarfdyi

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ycpD (D:)
mnypaepfriksvetvsmiprderlkkmqeagyntfllnskdiyidlltdsgtnamsdkq
wagmmmgdeayagsenfyhlertvqelfgfkhivpthqgrgaenllsqlaikpgqyvagn
myftttryhqekngavfvdivrdeahdaglniafkgdidlkklqklidekgaeniayicl
avtvnlaggqpvsmanmravrelteahgikvfydatrcvenayfikeqeqgfenksiaei
vhemfsyadgctmsgkkdclvniggflcmnddemfssakelvvvyegmpsygglagrdme
amaiglreamqyeyiehrvkqvrylgdklkaagvpivepvgghavfldarrfcehltqde
fpaqslaasiyvetgvrsmergiisagrnnvtgehhrpkletvrltiprrvytyahmdvv
adgiiklyqhkedirglkfiyepkqlrhftarfdyi