PDB entry 2yc6

View 2yc6 on RCSB PDB site
Description: crystal structure of a triple mutant (a198v, c202a and c222n) of triosephosphate isomerase from giardia lamblia complexed with 2- phosphoglycolic acid
Class: isomerase
Keywords: isomerase, glycolysis
Deposited on 2011-03-11, released 2012-03-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-05-29, with a file datestamp of 2013-05-24.
Experiment type: XRAY
Resolution: 1.45 Å
R-factor: 0.18801
AEROSPACI score: 0.65 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: triosephosphate isomerase
    Species: Giardia intestinalis [TaxId:5741]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P36186
      • engineered mutation (197)
      • engineered mutation (201)
      • engineered mutation (221)
    Domains in SCOPe 2.08: d2yc6a_
  • Heterogens: PGA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2yc6A (A:)
mparrpfiggnfkcngsldfikshvaaiaahkipdsvdvviapsavhlstaiaantskql
riaaqnvylegngawtgetsvemlqdmglkhvivghserrrimgetdeqsakkakralek
gmtvifcvgetlderkanrtmevniaqlealgkelgeskmlwkevviayepvwsigtgvv
atpeqaeevhvglrkwfvekvaaegaqhiriiyggsangsnneklgqcpnidgflvggas
lkpefmtmidiltktrt

    Sequence, based on observed residues (ATOM records): (download) 
    >2yc6A (A:)
parrpfiggnfkcngsldfikshvaaiaahkipdsvdvviapsavhlstaiaantskqlr
iaaqnvylegngawtgetsvemlqdmglkhvivghserrrimgetdeqsakkakralekg
mtvifcvgetlderkanrtmevniaqlealgkelgeskmlwkevviayepvwsigtgvva
tpeqaeevhvglrkwfvekvaaegaqhiriiyggsangsnneklgqcpnidgflvggasl
kpefmtmidiltktr