PDB entry 2yau

View 2yau on RCSB PDB site
Description: x-ray structure of the leishmania infantum tryopanothione reductase in complex with auranofin
Deposited on 2011-02-24, released 2012-01-11
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 3.5 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: trypanothione reductase
    Species: Leishmania infantum [TaxId:5671]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: trypanothione reductase
    Species: Leishmania infantum [TaxId:5671]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: FAD, NDP, AU, TS8, CL, SO4

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2yauA (A:)
mgsshhhhhhssglvprgshmsraydlvvlgagsggleagwnaavthkkkvavvdvqath
gpplfaalggtcvnvgcvpkklmvtgaqymdliresggfgwemdreslcpnwktliaakn
kvvnsinesyksmfadteglsfhmgfgalqdahtvvvrksedphsdvletldteyiliat
gswptrlgvpgdefcitsneafyledapkrmlcvgggyiavefagifngykpcggyvdlc
yrgdlilrgfdtevrksltkqlgangirvrtnlnptkitknedgsnhvhfndgteedydq
vmlaigrvprsqalqldkagvrtgkngavqvdaysktsvdniyaigdvtnrvmltpvain
egaafvetvfggkpratdhtkvacavfsippigtcgmteeeaaknyetvavyassftplm
hnisgskhkefmiriitnesngevlgvhmlgdsapeiiqsvgicmkmgakisdfhstigv
hptsaeelcsmrtpayfyesgkrveklssnl

    Sequence, based on observed residues (ATOM records):
    >2yauA (A:)
msraydlvvlgagsggleagwnaavthkkkvavvdvqathgpplfaalggtcvnvgcvpk
klmvtgaqymdliresggfgwemdreslcpnwktliaaknkvvnsinesyksmfadtegl
sfhmgfgalqdahtvvvrksedphsdvletldteyiliatgswptrlgvpgdefcitsne
afyledapkrmlcvgggyiavefagifngykpcggyvdlcyrgdlilrgfdtevrksltk
qlgangirvrtnlnptkitknedgsnhvhfndgteedydqvmlaigrvprsqalqldkag
vrtgkngavqvdaysktsvdniyaigdvtnrvmltpvainegaafvetvfggkpratdht
kvacavfsippigtcgmteeeaaknyetvavyassftplmhnisgskhkefmiriitnes
ngevlgvhmlgdsapeiiqsvgicmkmgakisdfhstigvhptsaeelcsmrtpayfyes
gkrvekls

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2yauB (B:)
mgsshhhhhhssglvprgshmsraydlvvlgagsggleagwnaavthkkkvavvdvqath
gpplfaalggtcvnvgcvpkklmvtgaqymdliresggfgwemdreslcpnwktliaakn
kvvnsinesyksmfadteglsfhmgfgalqdahtvvvrksedphsdvletldteyiliat
gswptrlgvpgdefcitsneafyledapkrmlcvgggyiavefagifngykpcggyvdlc
yrgdlilrgfdtevrksltkqlgangirvrtnlnptkitknedgsnhvhfndgteedydq
vmlaigrvprsqalqldkagvrtgkngavqvdaysktsvdniyaigdvtnrvmltpvain
egaafvetvfggkpratdhtkvacavfsippigtcgmteeeaaknyetvavyassftplm
hnisgskhkefmiriitnesngevlgvhmlgdsapeiiqsvgicmkmgakisdfhstigv
hptsaeelcsmrtpayfyesgkrveklssnl

    Sequence, based on observed residues (ATOM records):
    >2yauB (B:)
msraydlvvlgagsggleagwnaavthkkkvavvdvqathgpplfaalggtcvnvgcvpk
klmvtgaqymdliresggfgwemdreslcpnwktliaaknkvvnsinesyksmfadtegl
sfhmgfgalqdahtvvvrksedphsdvletldteyiliatgswptrlgvpgdefcitsne
afyledapkrmlcvgggyiavefagifngykpcggyvdlcyrgdlilrgfdtevrksltk
qlgangirvrtnlnptkitknedgsnhvhfndgteedydqvmlaigrvprsqalqldkag
vrtgkngavqvdaysktsvdniyaigdvtnrvmltpvainegaafvetvfggkpratdht
kvacavfsippigtcgmteeeaaknyetvavyassftplmhnisgskhkefmiriitnes
ngevlgvhmlgdsapeiiqsvgicmkmgakisdfhstigvhptsaeelcsmrtpayfyes
gkrvekls