PDB entry 2yac

View 2yac on RCSB PDB site
Description: crystal structure of polo-like kinase 1 in complex with nms-p937
Class: transferase
Keywords: transferase, ATP-binding, cell cycle, cell division, mitosis, nucleotide-binding, nucleus
Deposited on 2011-02-18, released 2011-04-06
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-05-11, with a file datestamp of 2011-05-06.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.213
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase PLK1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2yaca_
  • Heterogens: 937, ZN, TLA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2yacA (A:)
gpakeipevlvdprsrrryvrgrflgkggfakcfeisdadtkevfagkivpkslllkphq
rekmsmeisihrslahqhvvgfhgffedndfvfvvlelcrrrsllelhkrrkaltepear
yylrqivlgcqylhrnrvihrdlklgnlflnedlevkigdfglatkveydgerkktlcgt
pnyiapevlskkghsfevdvwsigcimytllvgkppfetsclketylrikkneysipkhi
npvaasliqkmlqtdptarptinellndefftsgyiparlpitcltipprfsiapssldp
snrkpltvlnk

    Sequence, based on observed residues (ATOM records): (download) 
    >2yacA (A:)
eipevlvdprsrrryvrgrflgkggfakcfeisdadtkevfagkivpkslllkphqrekm
smeisihrslahqhvvgfhgffedndfvfvvlelcrrrsllelhkrrkaltepearyylr
qivlgcqylhrnrvihrdlklgnlflnedlevkigdfglatkveydgerkktlcgtpnyi
apevlskkghsfevdvwsigcimytllvgkppfetsclketylrikkneysipkhinpva
asliqkmlqtdptarptinellndefftsgyiparlpitcltipprfsiap