PDB entry 2yac

View 2yac on RCSB PDB site
Description: Crystal structure of Polo-like kinase 1 in complex with NMS-P937
Class: transferase
Keywords: transferase, ATP-binding, cell cycle, cell division, mitosis, nucleotide-binding, nucleus
Deposited on 2011-02-18, released 2011-04-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-04-03, with a file datestamp of 2019-03-29.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase PLK1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2yaca_
  • Heterogens: 937, ZN, TLA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2yacA (A:)
    gpakeipevlvdprsrrryvrgrflgkggfakcfeisdadtkevfagkivpkslllkphq
    rekmsmeisihrslahqhvvgfhgffedndfvfvvlelcrrrsllelhkrrkaltepear
    yylrqivlgcqylhrnrvihrdlklgnlflnedlevkigdfglatkveydgerkktlcgt
    pnyiapevlskkghsfevdvwsigcimytllvgkppfetsclketylrikkneysipkhi
    npvaasliqkmlqtdptarptinellndefftsgyiparlpitcltipprfsiapssldp
    snrkpltvlnk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2yacA (A:)
    eipevlvdprsrrryvrgrflgkggfakcfeisdadtkevfagkivpkslllkphqrekm
    smeisihrslahqhvvgfhgffedndfvfvvlelcrrrsllelhkrrkaltepearyylr
    qivlgcqylhrnrvihrdlklgnlflnedlevkigdfglatkveydgerkktlcgtpnyi
    apevlskkghsfevdvwsigcimytllvgkppfetsclketylrikkneysipkhinpva
    asliqkmlqtdptarptinellndefftsgyiparlpitcltipprfsiap