PDB entry 2y8q
View 2y8q on RCSB PDB site
Description: Structure of the regulatory fragment of mammalian AMPK in complex with one ADP
Class: transferase
Keywords: transferase, ADP, nucleotide-binding
Deposited on
2011-02-09, released
2011-03-16
The last revision prior to the SCOPe 2.07 freeze date was dated
2012-11-28, with a file datestamp of
2012-11-23.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.234
AEROSPACI score: 0.24
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: 5'-amp-activated protein kinase catalytic subunit alpha-1
Species: Rattus norvegicus [TaxId:10116]
Database cross-references and differences (RAF-indexed):
- Uniprot P54645 (18-166)
- expression tag (15-17)
- expression tag (167-172)
Domains in SCOPe 2.07: d2y8qa1, d2y8qa2, d2y8qa3 - Chain 'B':
Compound: 5'-amp-activated protein kinase subunit beta-2
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d2y8qb_ - Chain 'E':
Compound: 5'-amp-activated protein kinase subunit gamma-1
Species: Rattus norvegicus [TaxId:10116]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d2y8qe1, d2y8qe2 - Heterogens: ADP, AMP, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2y8qA (A:)
mshhhhhhsglvprgsmawhlgirsqsrpndimaevcraikqldyewkvvnpyylrvrrk
npvtstfskmslqlyqvdsrtylldfrsiddeiteaksgtatpqrsgsisnyrscqrsds
daeaqgkpsevsltssvtsldsspvdvaprpgshtieffemcanliknsctvn
Sequence, based on observed residues (ATOM records): (download)
>2y8qA (A:)
smawhlgirsqsrpndimaevcraikqldyewkvvnpyylrvrrknpvtstfskmslqly
qvdsrtylldfrsiddevaprpgshtieffemcanliknsctvn
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2y8qB (B:)
mgpygqemyafrseerfksppilpphllqvilnkdtniscdpallpepnhvmlnhlyals
ikdsvmvlsathrykkkyvttllykpi
Sequence, based on observed residues (ATOM records): (download)
>2y8qB (B:)
gqemyafrseerfksppilpphllqvilnkdpnhvmlnhlyalsikdsvmvlsathrykk
kyvttllykpi
- Chain 'E':
Sequence, based on SEQRES records: (download)
>2y8qE (E:)
mesvaaesapapenehsqetpesnssvyttfmkshrcydliptssklvvfdtslqvkkaf
falvtngvraaplwdskkqsfvgmltitdfinilhryyksalvqiyeleehkietwrevy
lqdsfkplvcispnaslfdavsslirnkihrlpvidpesgntlyilthkrilkflklfit
efpkpefmsksleelqigtyaniamvrtttpvyvalgifvqhrvsalpvvdekgrvvdiy
skfdvinlaaektynnldvsvtkalqhrshyfegvlkcylhetleaiinrlveaevhrlv
vvdehdvvkgivslsdilqalvltggekkp
Sequence, based on observed residues (ATOM records): (download)
>2y8qE (E:)
snssvyttfmkshrcydliptssklvvfdtslqvkkaffalvtngvraaplwdskkqsfv
gmltitdfinilhryyksalvqiyeleehkietwrevylqdsfkplvcispnaslfdavs
slirnkihrlpvidpesgntlyilthkrilkflklfitefpkpefmsksleelqigtyan
iamvrtttpvyvalgifvqhrvsalpvvdekgrvvdiyskfdvinlaaektynnldvsvt
kalqhrshyfegvlkcylhetleaiinrlveaevhrlvvvdehdvvkgivslsdilqalv
ltgg