PDB entry 2y7s

View 2y7s on RCSB PDB site
Description: Structure of a designed meningococcal antigen (factor H binding protein, mutant G1) inducing broad protective immunity
Deposited on 2011-02-01, released 2011-07-27
The last revision was dated 2012-11-21, with a file datestamp of 2012-11-16.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.1879
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: factor h binding protein
    Species: Neisseria meningitidis serogroup B [TaxId:122586]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JXV4 (Start-247)
      • expression tag (248)
      • engineered mutation (127-128)
      • engineered mutation (133)
      • engineered mutation (135-136)
      • engineered mutation (139)
      • engineered mutation (141)
      • engineered mutation (143)
      • engineered mutation (165-166)
      • engineered mutation (184)
      • engineered mutation (187)
      • engineered mutation (189)
      • engineered mutation (192)
      • engineered mutation (196)
      • engineered mutation (201)
      • engineered mutation (203)
      • engineered mutation (205)
      • engineered mutation (207-209)
      • engineered mutation (222)
  • Chain 'B':
    Compound: factor h binding protein
    Species: Neisseria meningitidis serogroup B [TaxId:122586]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JXV4 (Start-247)
      • engineered mutation (127-128)
      • engineered mutation (133)
      • engineered mutation (135-136)
      • engineered mutation (139)
      • engineered mutation (141)
      • engineered mutation (143)
      • engineered mutation (165-166)
      • engineered mutation (184)
      • engineered mutation (187)
      • engineered mutation (189)
      • engineered mutation (192)
      • engineered mutation (196)
      • engineered mutation (201)
      • engineered mutation (203)
      • engineered mutation (205)
      • engineered mutation (207-209)
      • engineered mutation (222)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2y7sA (A:)
    mvaadigagladaltapldhkdkglqsltldqsvrkneklklaaqgaektygngdslntg
    klkndkvsrfdfirqievdgqlitlesgefqvykqshsaltafqteqiqdsehsgkmvak
    rqfrigdlggehtafnqlpdgkaeyrgtafgsddaggkltytidftkkqgngkiehlksp
    elnvelasaeikadgkshavilgdvrygseekgsyslgifggraqevagsaevktvngir
    higlaakqlehhhhhh
    

    Sequence, based on observed residues (ATOM records):
    >2y7sA (A:)
    gladaltapldhkdkglqsltldqsvrkneklklaaqgaektygngdslntgklkndkvs
    rfdfirqievdgqlitlesgefqvykqshsaltafqteqiqdsehsgkmvakrqfrigdl
    ggehtafnqlpdgkaeyrgtafgsddaggkltytidftkkqgngkiehlkspelnvelas
    aeikadgkshavilgdvrygseekgsyslgifggraqevagsaevktvngirhiglaakq
    l
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2y7sB (B:)
    mvaadigagladaltapldhkdkglqsltldqsvrkneklklaaqgaektygngdslntg
    klkndkvsrfdfirqievdgqlitlesgefqvykqshsaltafqteqiqdsehsgkmvak
    rqfrigdlggehtafnqlpdgkaeyrgtafgsddaggkltytidftkkqgngkiehlksp
    elnvelasaeikadgkshavilgdvrygseekgsyslgifggraqevagsaevktvngir
    higlaakqlehhhhhh
    

    Sequence, based on observed residues (ATOM records):
    >2y7sB (B:)
    gladaltapldhkdkglqsltldqsvrkneklklaaqgaektygngdslntgklkndkvs
    rfdfirqievdgqlitlesgefqvykqshsaltafqteqiqdsehsgkmvakrqfrigdl
    ggehtafnqlpdgkaeyrgtafgsddaggkltytidftkkqgngkiehlkspelnvelas
    aeikadgkshavilgdvrygseekgsyslgifggraqevagsaevktvngirhiglaakq