PDB entry 2y68

View 2y68 on RCSB PDB site
Description: structure-based design of a new series of d-glutamic acid-based inhibitors of bacterial murd ligase
Deposited on 2011-01-20, released 2011-06-08
The last revision was dated 2018-02-28, with a file datestamp of 2018-02-23.
Experiment type: XRAY
Resolution: 1.49 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: udp-n-acetylmuramoylalanine--d-glutamate ligase
    Species: Escherichia coli K-12 [TaxId:83333]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14900 (Start-437)
      • expression tag (438-439)
  • Heterogens: T04, DMS, AZI, SO4, CL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2y68A (A:)
madyqgknvviiglgltglscvdfflargvtprvmdtrmtppgldklpeaverhtgslnd
ewlmaadlivaspgialahpslsaaadagieivgdielfcreaqapivaitgsngkstvt
tlvgemakaagvnvgvggniglpalmllddecelyvlelssfqlettsslqavaatilnv
tedhmdrypfglqqyraaklriyenakvcvvnaddaltmpirgadercvsfgvnmgdyhl
nhqqgetwlrvkgekvlnvkemklsgqhnytnalaalaladaaglprasslkalttftgl
phrfevvlehngvrwindskatnvgsteaalnglhvdgtlhlllggdgksadfsplaryl
ngdnvrlycfgrdgaqlaalrpevaeqtetmeqamrllaprvqpgdmvllspacasldqf
knfeqrgnefarlakelgshhhhhh

    Sequence, based on observed residues (ATOM records):
    >2y68A (A:)
adyqgknvviiglgltglscvdfflargvtprvmdtrmtppgldklpeaverhtgslnde
wlmaadlivaspgialahpslsaaadagieivgdielfcreaqapivaitgsngkstvtt
lvgemakaagvnvgvggniglpalmllddecelyvlelssfqlettsslqavaatilnvt
edhmdrypfglqqyraaklriyenakvcvvnaddaltmpirrcvsfgvnmgdyhlnhqqg
etwlrvkgekvlnvkemklsgqhnytnalaalaladaaglprasslkalttftglphrfe
vvlehngvrwindskatnvgsteaalnglhvdgtlhlllggdgksadfsplarylngdnv
rlycfgrdgaqlaalrpevaeqtetmeqamrllaprvqpgdmvllspacasldqfknfeq
rgnefarlakelgsh