PDB entry 2y41

View 2y41 on RCSB PDB site
Description: structure of isopropylmalate dehydrogenase from thermus thermophilus - complex with ipm and mn
Class: oxidoreductase
Keywords: oxidoreductase, leub, leucine biosynthesis
Deposited on 2011-01-04, released 2011-01-19
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-01-19, with a file datestamp of 2011-01-14.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.18682
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-isopropylmalate dehydrogenase
    Species: Thermus thermophilus [TaxId:274]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5SIY4 (3-347)
      • expression tag (2)
      • expression tag (348)
    Domains in SCOPe 2.01: d2y41a_
  • Chain 'B':
    Compound: 3-isopropylmalate dehydrogenase
    Species: Thermus thermophilus [TaxId:274]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5SIY4 (3-347)
      • expression tag (2)
      • expression tag (348)
    Domains in SCOPe 2.01: d2y41b_
  • Heterogens: IPM, MN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2y41A (A:)
masmkvavlpgdgigpevteaalkvlraldeaeglglayevfpfggaaidafgepfpept
rkgveeaeavllgsvggpkwdglprkirpetgllslrksqdlfanlrpakvfpglerlsp
lkeeiargvdvlivreltggiyfgeprgmseaeawnteryskpevervarvafeaarkrr
khvvsvdkanvlevgefwrktveevgrgypdvalehqyvdamamhlvrsparfdvvvtgn
ifgdilsdlasvlpgslgllpsaslgrgtpvfepvhgsapdiagkgianptaailsaamm
lehafglvelarkvedavakalletpppdlggsagteaftatvlrhlaaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2y41A (A:)
smkvavlpgdgigpevteaalkvlraldeaeglglayevfpfggaaidafgepfpeptrk
gveeaeavllgsvggpkwdglprkirpetgllslrksqdlfanlrpakvfpglerlsplk
eeiargvdvlivreltggiyfgeprgmseaeawnteryskpevervarvafeaarkrrkh
vvsvdkanvlevgefwrktveevgrgypdvalehqyvdamamhlvrsparfdvvvtgnif
gdilsdlasvlpgslgllpsaslgrgtpvfepvhgsapdiagkgianptaailsaammle
hafglvelarkvedavakalletpppdlggsagteaftatvlrhlaa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2y41B (B:)
masmkvavlpgdgigpevteaalkvlraldeaeglglayevfpfggaaidafgepfpept
rkgveeaeavllgsvggpkwdglprkirpetgllslrksqdlfanlrpakvfpglerlsp
lkeeiargvdvlivreltggiyfgeprgmseaeawnteryskpevervarvafeaarkrr
khvvsvdkanvlevgefwrktveevgrgypdvalehqyvdamamhlvrsparfdvvvtgn
ifgdilsdlasvlpgslgllpsaslgrgtpvfepvhgsapdiagkgianptaailsaamm
lehafglvelarkvedavakalletpppdlggsagteaftatvlrhlaaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2y41B (B:)
smkvavlpgdgigpevteaalkvlraldeaeglglayevfpfggaaidafgepfpeptrk
gveeaeavllgsvggpkwdglprkirpetgllslrksqdlfanlrpakvfpglerlsplk
eeiargvdvlivreltggiyfgeprgmseaeawnteryskpevervarvafeaarkrrkh
vvsvdkanvlevgefwrktveevgrgypdvalehqyvdamamhlvrsparfdvvvtgnif
gdilsdlasvlpgslgllpsaslgrgtpvfepvhgsapdiagkgianptaailsaammle
hafglvelarkvedavakalletpppdlggsagteaftatvlrhlaa