PDB entry 2y40

View 2y40 on RCSB PDB site
Description: Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - complex with Mn
Class: oxidoreductase
Keywords: oxidoreductase, leub, leucine biosynthesis
Deposited on 2011-01-04, released 2011-01-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-17, with a file datestamp of 2019-07-12.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-isopropylmalate dehydrogenase
    Species: Thermus thermophilus [TaxId:274]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5SIY4 (3-347)
      • expression tag (348-349)
    Domains in SCOPe 2.08: d2y40a1, d2y40a2
  • Chain 'B':
    Compound: 3-isopropylmalate dehydrogenase
    Species: Thermus thermophilus [TaxId:274]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5SIY4 (3-347)
      • expression tag (348)
    Domains in SCOPe 2.08: d2y40b1, d2y40b2
  • Heterogens: MN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2y40A (A:)
masmkvavlpgdgigpevteaalkvlraldeaeglglayevfpfggaaidafgepfpept
rkgveeaeavllgsvggpkwdglprkirpetgllslrksqdlfanlrpakvfpglerlsp
lkeeiargvdvlivreltggiyfgeprgmseaeawnteryskpevervarvafeaarkrr
khvvsvdkanvlevgefwrktveevgrgypdvalehqyvdamamhlvrsparfdvvvtgn
ifgdilsdlasvlpgslgllpsaslgrgtpvfepvhgsapdiagkgianptaailsaamm
lehafglvelarkvedavakalletpppdlggsagteaftatvlrhlaaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2y40A (A:)
mkvavlpgdgigpevteaalkvlraldeaeglglayevfpfggaaidafgepfpeptrkg
veeaeavllgsvggpkwdglprkirpetgllslrksqdlfanlrpakvfpglerlsplke
eiargvdvlivreltggiyfgeprgmseaeawnteryskpevervarvafeaarkrrkhv
vsvdkanvlevgefwrktveevgrgypdvalehqyvdamamhlvrsparfdvvvtgnifg
dilsdlasvlpgslgllpsaslgrgtpvfepvhgsapdiagkgianptaailsaammleh
afglvelarkvedavakalletpppdlggsagteaftatvlrhlaaa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2y40B (B:)
masmkvavlpgdgigpevteaalkvlraldeaeglglayevfpfggaaidafgepfpept
rkgveeaeavllgsvggpkwdglprkirpetgllslrksqdlfanlrpakvfpglerlsp
lkeeiargvdvlivreltggiyfgeprgmseaeawnteryskpevervarvafeaarkrr
khvvsvdkanvlevgefwrktveevgrgypdvalehqyvdamamhlvrsparfdvvvtgn
ifgdilsdlasvlpgslgllpsaslgrgtpvfepvhgsapdiagkgianptaailsaamm
lehafglvelarkvedavakalletpppdlggsagteaftatvlrhlaaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2y40B (B:)
mkvavlpgdgigpevteaalkvlraldeaeglglayevfpfggaaidafgepfpeptrkg
veeaeavllgsvggpkwdglprkirpetgllslrksqdlfanlrpakvfpglerlsplke
eiargvdvlivreltggiyfgeprgmseaeawnteryskpevervarvafeaarkrrkhv
vsvdkanvlevgefwrktveevgrgypdvalehqyvdamamhlvrsparfdvvvtgnifg
dilsdlasvlpgslgllpsaslgrgtpvfepvhgsapdiagkgianptaailsaammleh
afglvelarkvedavakalletpppdlggsagteaftatvlrhlaa