PDB entry 2y1x

View 2y1x on RCSB PDB site
Description: crystal structure of coactivator associated arginine methyltransferase 1 (carm1) in complex with sinefungin and indole inhibitor
Class: transferase
Keywords: histone modification, transferase
Deposited on 2010-12-10, released 2011-03-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-05-25, with a file datestamp of 2011-05-20.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.21
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: histone-arginine methyltransferase carm1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2y1xa_
  • Chain 'B':
    Compound: histone-arginine methyltransferase carm1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: histone-arginine methyltransferase carm1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: histone-arginine methyltransferase carm1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SAH, 845, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2y1xA (A:)
svfserteessavqyfqfygylsqqqnmmqdyvrtgtyqrailqnhtdfkdkivldvgcg
sgilsffaaqagarkiyaveastmaqhaevlvksnnltdrivvipgkveevslpeqvdii
isepmgymlfnermlesylhakkylkpsgnmfptigdvhlapftdeqlymeqftkanfwy
qpsfhgvdlsalrgaavdeyfrqpvvdtfdirilmaksvkytvnfleakegdlhrieipf
kfhmlhsglvhglafwfdvafigsimtvwlstapteplthwyqvrclfqsplfakagdtl
sgtclliankrqsydisivaqvdqtgskssnlldlknpffrytgttps

    Sequence, based on observed residues (ATOM records): (download) 
    >2y1xA (A:)
svfserteessavqyfqfygylsqqqnmmqdyvrtgtyqrailqnhtdfkdkivldvgcg
sgilsffaaqagarkiyaveastmaqhaevlvksnnltdrivvipgkveevslpeqvdii
isepmgymlfnermlesylhakkylkpsgnmfptigdvhlapftdeqlymeqftkanfwy
qpsfhgvdlsalrgaavdeyfrqpvvdtfdirilmaksvkytvnfleakegdlhrieipf
kfhmlhsglvhglafwfdvafigsimtvwlstapteplthwyqvrclfqsplfakagdtl
sgtclliankrqsydisivaqvdqtgskssnlldlknpffryt

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.