PDB entry 2y1l

View 2y1l on RCSB PDB site
Description: Caspase-8 in Complex with DARPin-8.4
Deposited on 2010-12-08, released 2011-12-28
The last revision was dated 2014-03-12, with a file datestamp of 2014-03-07.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.182
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: caspase-8
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: caspase-8
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: caspase-8
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: caspase-8
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: darpin-8.4
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 2Y1L
  • Chain 'F':
    Compound: darpin-8.4
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 2Y1L
  • Chain 'G':
    Compound: ac-ietd-cho
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 2Y1L (0-3)
  • Chain 'H':
    Compound: ac-ietd-cho
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 2Y1L (0-3)
  • Heterogens: SO4, EDO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2y1lA (A:)
mgesqtldkvyqmkskprgycliinnhnfakarekvpklhsirdrngthldagaltttfe
elhfeikphddctveqiyeilkiyqlmdhsnmdcficcilshgdkgiiygtdgqeapiye
ltsqftglkcpslagkpkvffiqacqgdnyqkgipvetd

    Sequence, based on observed residues (ATOM records):
    >2y1lA (A:)
ldkvyqmkskprgycliinnhnfakarekvpklhsirdrngthldagaltttfeelhfei
kphddctveqiyeilkiyqlmdhsnmdcficcilshgdkgiiygtdgqeapiyeltsqft
glkcpslagkpkvffiqacqgdnyqkgipv

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2y1lB (B:)
eeqpylemdlsspqtryipdeadfllgmatvnncvsyrnpaegtwyiqslcqslrercpr
gddiltiltevnyevsnkddkknmgkqmpqptftlrkklvfpsd

    Sequence, based on observed residues (ATOM records):
    >2y1lB (B:)
yipdeadfllgmatvnncvsyrnpaegtwyiqslcqslrercprgddiltiltevnyevs
nkddkknmgkqmpqptftlrkklvfps

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2y1lC (C:)
mgesqtldkvyqmkskprgycliinnhnfakarekvpklhsirdrngthldagaltttfe
elhfeikphddctveqiyeilkiyqlmdhsnmdcficcilshgdkgiiygtdgqeapiye
ltsqftglkcpslagkpkvffiqacqgdnyqkgipvetd

    Sequence, based on observed residues (ATOM records):
    >2y1lC (C:)
dkvyqmkskprgycliinnhnfakarekvpklhsirdrngthldagaltttfeelhfeik
phddctveqiyeilkiyqlmdhsnmdcficcilshgdkgiiygtdgqeapiyeltsqftg
lkcpslagkpkvffiqacqgdnyqkgip

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2y1lD (D:)
eeqpylemdlsspqtryipdeadfllgmatvnncvsyrnpaegtwyiqslcqslrercpr
gddiltiltevnyevsnkddkknmgkqmpqptftlrkklvfpsd

    Sequence, based on observed residues (ATOM records):
    >2y1lD (D:)
tryipdeadfllgmatvnncvsyrnpaegtwyiqslcqslrercprgddiltiltevnye
vsnkddkknmgkqmpqptftlrkklvfpsd

  • Chain 'E':
    Sequence, based on SEQRES records:
    >2y1lE (E:)
mrgshhhhhhgsdlgkklleaaragrddevrilmangadvnaedasgwtplhlaafnghl
eivevllkngadvnavdhagmtplrlaalfghleivevllkngadvnandmeghtplhla
amfghleivevllkngadvnaqdkfgktafdisidngnedlaeilqkln

    Sequence, based on observed residues (ATOM records):
    >2y1lE (E:)
dlgkklleaaragrddevrilmangadvnaedasgwtplhlaafnghleivevllkngad
vnavdhagmtplrlaalfghleivevllkngadvnandmeghtplhlaamfghleivevl
lkngadvnaqdkfgktafdisidngnedlaeilqkl

  • Chain 'F':
    Sequence, based on SEQRES records:
    >2y1lF (F:)
mrgshhhhhhgsdlgkklleaaragrddevrilmangadvnaedasgwtplhlaafnghl
eivevllkngadvnavdhagmtplrlaalfghleivevllkngadvnandmeghtplhla
amfghleivevllkngadvnaqdkfgktafdisidngnedlaeilqkln

    Sequence, based on observed residues (ATOM records):
    >2y1lF (F:)
dlgkklleaaragrddevrilmangadvnaedasgwtplhlaafnghleivevllkngad
vnavdhagmtplrlaalfghleivevllkngadvnandmeghtplhlaamfghleivevl
lkngadvnaqdkfgktafdisidngnedlaeilqkl

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records:
    >2y1lG (G:)
ietd

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records:
    >2y1lH (H:)
ietd