PDB entry 2y1f

View 2y1f on RCSB PDB site
Description: x-ray structure of 1-deoxy-d-xylulose 5-phosphate reductoisomerase, dxr, rv2870c, from mycobacterium tuberculosis, in complex with a 3,4- dichlorophenyl-substituted fosmidomycin analogue, manganese and nadph.
Deposited on 2010-12-08, released 2011-06-29
The last revision was dated 2018-01-17, with a file datestamp of 2018-01-12.
Experiment type: XRAY
Resolution: 1.96 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 1-deoxy-D-xylulose 5-phosphate reductoisomerase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: 1-deoxy-D-xylulose 5-phosphate reductoisomerase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 34F, NDP, MN, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2y1fA (A:)
tmahhhhhhvtnstdgradgrlrvvvlgstgsigtqalqviadnpdrfevvglaaggahl
dtllrqraqtgvtniavadehaaqrvgdipyhgsdaatrlveqteadvvlnalvgalglr
ptlaalktgarlalankeslvaggslvlraarpgqivpvdsehsalaqclrggtpdevak
lvltasggpfrgwsaadlehvtpeqagahptwsmgpmntlnsaslvnkgleviethllfg
ipydridvvvhpqsiihsmvtfidgstiaqasppdmklpislalgwprrvsgaaaacdfh
tasswefepldtdvfpavelarqagvaggcmtavynaaneeaaaaflagrigfpaivgii
advlhaadqwavepatvddvldaqrwareraqravsgm

    Sequence, based on observed residues (ATOM records):
    >2y1fA (A:)
grlrvvvlgstgsigtqalqviadnpdrfevvglaaggahldtllrqraqtgvtniavad
ehaaqrvgdipyhgsdaatrlveqteadvvlnalvgalglrptlaalktgarlalankes
lvaggslvlraarpgqivpvdsehsalaqclrggtpdevaklvltasggpfrgwsaadle
hvtpeqagmgpmntlnsaslvnkgleviethllfgipydridvvvhpqsiihsmvtfidg
stiaqasppdmklpislalgwprrvsgaaaacdfhtasswefepldtdvfpavelarqag
vaggcmtavynaaneeaaaaflagrigfpaivgiiadvlhaadqwavepatvddvldaqr
wareraqravsgm

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2y1fB (B:)
tmahhhhhhvtnstdgradgrlrvvvlgstgsigtqalqviadnpdrfevvglaaggahl
dtllrqraqtgvtniavadehaaqrvgdipyhgsdaatrlveqteadvvlnalvgalglr
ptlaalktgarlalankeslvaggslvlraarpgqivpvdsehsalaqclrggtpdevak
lvltasggpfrgwsaadlehvtpeqagahptwsmgpmntlnsaslvnkgleviethllfg
ipydridvvvhpqsiihsmvtfidgstiaqasppdmklpislalgwprrvsgaaaacdfh
tasswefepldtdvfpavelarqagvaggcmtavynaaneeaaaaflagrigfpaivgii
advlhaadqwavepatvddvldaqrwareraqravsgm

    Sequence, based on observed residues (ATOM records):
    >2y1fB (B:)
grlrvvvlgstgsigtqalqviadnpdrfevvglaaggahldtllrqraqtgvtniavad
ehaaqrvgdipyhgsdaatrlveqteadvvlnalvgalglrptlaalktgarlalankes
lvaggslvlraarpgqivpvdsehsalaqclrggtpdevaklvltasggpfrgwsaadle
hvtpeqagahptwsmgpmntlnsaslvnkgleviethllfgipydridvvvhpqsiihsm
vtfidgstiaqasppdmklpislalgwprrvsgaaaacdfhtasswefepldtdvfpave
larqagvaggcmtavynaaneeaaaaflagrigfpaivgiiadvlhaadqwavepatvdd
vldaqrwareraqravsgm