PDB entry 2y0p

View 2y0p on RCSB PDB site
Description: crystal structure of the suca domain of mycobacterium smegmatis alpha-ketoglutarate decarboxylase in complex with the enamine-thdp intermediate and acetyl-coa
Deposited on 2010-12-07, released 2011-06-15
The last revision was dated 2011-10-12, with a file datestamp of 2011-10-07.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.198
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-oxoglutarate decarboxylase
    Species: MYCOBACTERIUM SMEGMATIS [TaxId:246196]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: 2-oxoglutarate decarboxylase
    Species: MYCOBACTERIUM SMEGMATIS [TaxId:246196]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: 2-oxoglutarate decarboxylase
    Species: MYCOBACTERIUM SMEGMATIS [TaxId:246196]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: 2-oxoglutarate decarboxylase
    Species: MYCOBACTERIUM SMEGMATIS [TaxId:246196]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: TD7, MG, ACO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2y0pA (A:)
    gdsiedknarvieliaayrnrghlmadidplrldntrfrshpdldvnshgltlwdldref
    kvdgfagvqrkklrdilsvlrdaycrhvgveythilepeqqrwiqervetkhdkptvaeq
    kyilsklnaaeafetflqtkyvgqkrfslegaetvipmmdavidqcaehgldevviamph
    rgrlnvlanivgkpysqifsefegnlnpsqahgsgdvkyhlgatgtyiqmfgdndievsl
    tanpshleavdpvleglvrakqdlldtgeegsdnrfsvvplmlhgdaafagqgvvaetln
    lallrgyrtggtihivvnnqigfttaptdsrsseyctdvakmigapifhvngddpeacaw
    varlavdfrqafkkdvvidmlcyrrrghnegddpsmtqpymydvidtkrgsrkayteali
    grgdismkeaedalrdyqgqlervfnevrelekheiepsesveadqqipsklatavdkam
    lqrigdahlalpegftvhprvrpvlekrremayegridwafaellalgsliaegklvrls
    gqdtqrgtftqrhavivdrktgeeftplqllatnpdgtptggkflvynsalsefaavgfe
    ygysvgnpdamvlweaqfgdfvngaqsiidefissgeakwgqlsdvvlllphghegqgpd
    htsgrierflqlwaegsmtiampstpanyfhllrrhgkdgiqrplivftpksmlrnkaav
    sdirdfteskfrsvleepmytdgegdrnkvtrllltsgkiyyelaarkakenredvaivr
    ieqlaplprrrlaetldrypnvkekfwvqeepanqgawpsfgltlpeilpdhftglkris
    rramsapssgsskvhaveqqeildtafg
    

    Sequence, based on observed residues (ATOM records):
    >2y0pA (A:)
    dsiedknarvieliaayrnrghlmadidplrldltlwdldrefkvdvqrkklrdilsvlr
    daycrhvgveythilepeqqrwiqervetkhdkptvaeqkyilsklnaaeafetflqtky
    vgqkrfslegaetvipmmdavidqcaehgldevviamphrgrlnvlanivgkpysqifse
    fegnlnpsqahgsgdvkyhlgatgtyiqmfgdndievsltanpshleavdpvleglvrak
    qdlldtgeegsdnrfsvvplmlhgdaafagqgvvaetlnlallrgyrtggtihivvnnqi
    gfttaptdsrsseyctdvakmigapifhvngddpeacawvarlavdfrqafkkdvvidml
    cyrrrghnegddpsmtqpymydvidtkrgsrkaytealigrgdismkeaedalrdyqgql
    ervfnevrelekheiepsesveadqqipsklatavdkamlqrigdahlalpegftvhprv
    rpvlekrremayegridwafaellalgsliaegklvrlsgqdtqrgtftqrhavivdrkt
    geeftplqllatnpdgtptggkflvynsalsefaavgfeygysvgnpdamvlweaqfgdf
    vngaqsiidefissgeakwgqlsdvvlllphghegqgpdhtsgrierflqlwaegsmtia
    mpstpanyfhllrrhgkdgiqrplivftpksmlrnkaavsdirdfteskfrsvleepmyt
    dgegdrnkvtrllltsgkiyyelaarkakenredvaivrieqlaplprrrlaetldrypn
    vkekfwvqeepanqgawpsfgltlpeilpdhftglkrisrramsapssgsskvhaveqqe
    ildtafg
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2y0pB (B:)
    gdsiedknarvieliaayrnrghlmadidplrldntrfrshpdldvnshgltlwdldref
    kvdgfagvqrkklrdilsvlrdaycrhvgveythilepeqqrwiqervetkhdkptvaeq
    kyilsklnaaeafetflqtkyvgqkrfslegaetvipmmdavidqcaehgldevviamph
    rgrlnvlanivgkpysqifsefegnlnpsqahgsgdvkyhlgatgtyiqmfgdndievsl
    tanpshleavdpvleglvrakqdlldtgeegsdnrfsvvplmlhgdaafagqgvvaetln
    lallrgyrtggtihivvnnqigfttaptdsrsseyctdvakmigapifhvngddpeacaw
    varlavdfrqafkkdvvidmlcyrrrghnegddpsmtqpymydvidtkrgsrkayteali
    grgdismkeaedalrdyqgqlervfnevrelekheiepsesveadqqipsklatavdkam
    lqrigdahlalpegftvhprvrpvlekrremayegridwafaellalgsliaegklvrls
    gqdtqrgtftqrhavivdrktgeeftplqllatnpdgtptggkflvynsalsefaavgfe
    ygysvgnpdamvlweaqfgdfvngaqsiidefissgeakwgqlsdvvlllphghegqgpd
    htsgrierflqlwaegsmtiampstpanyfhllrrhgkdgiqrplivftpksmlrnkaav
    sdirdfteskfrsvleepmytdgegdrnkvtrllltsgkiyyelaarkakenredvaivr
    ieqlaplprrrlaetldrypnvkekfwvqeepanqgawpsfgltlpeilpdhftglkris
    rramsapssgsskvhaveqqeildtafg
    

    Sequence, based on observed residues (ATOM records):
    >2y0pB (B:)
    dknarvieliaayrnrghlmadidplrldnwdldrefkvqrkklrdilsvlrdaycrhvg
    veythilepeqqrwiqervetkhdkptvaeqkyilsklnaaeafetflqtkyvgqkrfsl
    egaetvipmmdavidqcaehgldevviamphrgrlnvlanivgkpysqifsefegnlnps
    qahgsgdvkyhlgatgtyiqmfgdndievsltanpshleavdpvleglvrakqdlldtge
    egsdnrfsvvplmlhgdaafagqgvvaetlnlallrgyrtggtihivvnnqigfttaptd
    srsseyctdvakmigapifhvngddpeacawvarlavdfrqafkkdvvidmlcyrrrghn
    egddpsmtqpymydvidtkrgsrkaytealigrgdismkeaedalrdyqgqlervfnevr
    elekheiepsesveadqqipsklatavdkamlqrigdahlalpegftvhprvrpvlekrr
    emayegridwafaellalgsliaegklvrlsgqdtqrgtftqrhavivdrktgeeftplq
    llatnpdgtptggkflvynsalsefaavgfeygysvgnpdamvlweaqfgdfvngaqsii
    defissgeakwgqlsdvvlllphghegqgpdhtsgrierflqlwaegsmtiampstpany
    fhllrrhgkdgiqrplivftpksmlrnkaavsdirdfteskfrsvleepmytdgegdrnk
    vtrllltsgkiyyelaarkakenredvaivrieqlaplprrrlaetldrypnvkekfwvq
    eepanqgawpsfgltlpeilpdhftglkrisrramsapssgsskvhaveqqeildtafg
    

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2y0pC (C:)
    gdsiedknarvieliaayrnrghlmadidplrldntrfrshpdldvnshgltlwdldref
    kvdgfagvqrkklrdilsvlrdaycrhvgveythilepeqqrwiqervetkhdkptvaeq
    kyilsklnaaeafetflqtkyvgqkrfslegaetvipmmdavidqcaehgldevviamph
    rgrlnvlanivgkpysqifsefegnlnpsqahgsgdvkyhlgatgtyiqmfgdndievsl
    tanpshleavdpvleglvrakqdlldtgeegsdnrfsvvplmlhgdaafagqgvvaetln
    lallrgyrtggtihivvnnqigfttaptdsrsseyctdvakmigapifhvngddpeacaw
    varlavdfrqafkkdvvidmlcyrrrghnegddpsmtqpymydvidtkrgsrkayteali
    grgdismkeaedalrdyqgqlervfnevrelekheiepsesveadqqipsklatavdkam
    lqrigdahlalpegftvhprvrpvlekrremayegridwafaellalgsliaegklvrls
    gqdtqrgtftqrhavivdrktgeeftplqllatnpdgtptggkflvynsalsefaavgfe
    ygysvgnpdamvlweaqfgdfvngaqsiidefissgeakwgqlsdvvlllphghegqgpd
    htsgrierflqlwaegsmtiampstpanyfhllrrhgkdgiqrplivftpksmlrnkaav
    sdirdfteskfrsvleepmytdgegdrnkvtrllltsgkiyyelaarkakenredvaivr
    ieqlaplprrrlaetldrypnvkekfwvqeepanqgawpsfgltlpeilpdhftglkris
    rramsapssgsskvhaveqqeildtafg
    

    Sequence, based on observed residues (ATOM records):
    >2y0pC (C:)
    edknarvieliaayrnrghlmadidplrldntrfnshgltlwdldrefkvdgfagvqrkk
    lrdilsvlrdaycrhvgveythilepeqqrwiqervetkhdkptvaeqkyilsklnaaea
    fetflqtkyvgqkrfslegaetvipmmdavidqcaehgldevviamphrgrlnvlanivg
    kpysqifsefegnlnpsqahgsgdvkyhlgatgtyiqmfgdndievsltanpshleavdp
    vleglvrakqdlldtgeegsdnrfsvvplmlhgdaafagqgvvaetlnlallrgyrtggt
    ihivvnnqigfttaptdsrsseyctdvakmigapifhvngddpeacawvarlavdfrqaf
    kkdvvidmlcyrrrghnegddpsmtqpymydvidtkrgsrkaytealigrgdismkeaed
    alrdyqgqlervfnevrelekheiepsesveadqqipsklatavdkamlqrigdahlalp
    egftvhprvrpvlekrremayegridwafaellalgsliaegklvrlsgqdtqrgtftqr
    havivdrktgeeftplqllatnpdgtptggkflvynsalsefaavgfeygysvgnpdamv
    lweaqfgdfvngaqsiidefissgeakwgqlsdvvlllphghegqgpdhtsgrierflql
    waegsmtiampstpanyfhllrrhgkdgiqrplivftpksmlrnkaavsdirdfteskfr
    svleepmytdgegdrnkvtrllltsgkiyyelaarkakenredvaivrieqlaplprrrl
    aetldrypnvkekfwvqeepanqgawpsfgltlpeilpdhftglkrisrramsapssgss
    kvhaveqqeildtafg
    

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2y0pD (D:)
    gdsiedknarvieliaayrnrghlmadidplrldntrfrshpdldvnshgltlwdldref
    kvdgfagvqrkklrdilsvlrdaycrhvgveythilepeqqrwiqervetkhdkptvaeq
    kyilsklnaaeafetflqtkyvgqkrfslegaetvipmmdavidqcaehgldevviamph
    rgrlnvlanivgkpysqifsefegnlnpsqahgsgdvkyhlgatgtyiqmfgdndievsl
    tanpshleavdpvleglvrakqdlldtgeegsdnrfsvvplmlhgdaafagqgvvaetln
    lallrgyrtggtihivvnnqigfttaptdsrsseyctdvakmigapifhvngddpeacaw
    varlavdfrqafkkdvvidmlcyrrrghnegddpsmtqpymydvidtkrgsrkayteali
    grgdismkeaedalrdyqgqlervfnevrelekheiepsesveadqqipsklatavdkam
    lqrigdahlalpegftvhprvrpvlekrremayegridwafaellalgsliaegklvrls
    gqdtqrgtftqrhavivdrktgeeftplqllatnpdgtptggkflvynsalsefaavgfe
    ygysvgnpdamvlweaqfgdfvngaqsiidefissgeakwgqlsdvvlllphghegqgpd
    htsgrierflqlwaegsmtiampstpanyfhllrrhgkdgiqrplivftpksmlrnkaav
    sdirdfteskfrsvleepmytdgegdrnkvtrllltsgkiyyelaarkakenredvaivr
    ieqlaplprrrlaetldrypnvkekfwvqeepanqgawpsfgltlpeilpdhftglkris
    rramsapssgsskvhaveqqeildtafg
    

    Sequence, based on observed residues (ATOM records):
    >2y0pD (D:)
    siedknarvieliaayrnrghlmadidplrldtlwdldrefkrkklrdilsvlrdaycrh
    vgveythilepeqqrwiqervetkhdkptvaeqkyilsklnaaeafetflqtkyvgqkrf
    slegaetvipmmdavidqcaehgldevviamphrgrlnvlanivgkpysqifsefegnln
    hgsgdvkyhlgatgtyiqmfgdndievsltanpshleavdpvleglvrakqdlldtgeeg
    sdnrfsvvplmlhgdaafagqgvvaetlnlallrgyrtggtihivvnnqigfttaptdsr
    sseyctdvakmigapifhvngddpeacawvarlavdfrqafkkdvvidmlcyrrrghneg
    ddpsmtqpymydvidtkrgsrkaytealigrgdismkeaedalrdyqgqlervfnevrel
    ekheiepsesveadqqipsklatavdkamlqrigdahlalpegftvhprvrpvlekrrem
    ayegridwafaellalgsliaegklvrlsgqdtqrgtftqrhavivdrktgeeftplqll
    atnpdgtptggkflvynsalsefaavgfeygysvgnpdamvlweaqfgdfvngaqsiide
    fissgeakwgqlsdvvlllphghegqgpdhtsgrierflqlwaegsmtiampstpanyfh
    llrrhgkdgiqrplivftpksmlrnkaavsdirdfteskfrsvleepmytdgegdrnkvt
    rllltsgkiyyelaarkakenredvaivrieqlaplprrrlaetldrypnvkekfwvqee
    panqgawpsfgltlpeilpdhftglkrisrramsapssgsskvhaveqqeildtafg